#for_researcher

Musculoskeletal adaptations to strength training in frail elderly: a matter of quantity or quality?

S.N. Aas, M. Breit, S. Karsrud, et al.

J Cachexia Sarcopenia Muscle. 2020 Feb 24. doi: 10.1002/jcsm.12543. [Epub ahead of print]

The aim of this study was to investigate the effect of heavy-load strength training on a broad number of factors related to specific strength in frail elderly.

Spanish

Sex-different associations between serum homocysteine, high-sensitivity C-reactive protein and sarcopenia: Results from I-Lan Longitudinal Aging Study

W.J. Lee, L.N. Peng, C.H. Loh, et al.

Exp Gerontol. 2020 Apr;132:110832. doi: 10.1016/j.exger.2020.110832. Epub 2020 Jan 8.

Both serum homocysteine and high sensitivity C - reactive protein (hsCRP) are inflammatory markers related to vascular aging. Little was known about relationship between hsCRP and homocysteine and sarcopenia. The study aimed to explore the association between these two biomarkers and sarcopenia and its components.

Spanish

Which one came first: movement behavior or frailty? A cross-lagged panel model in the Toledo Study for Healthy Aging

A. Mañas, B. Del Pozo-Cruz, I. Rodríguez-Gómez, et al.

J Cachexia Sarcopenia Muscle. 2020 Jan 8. doi: 10.1002/jcsm.12511. [Epub ahead of print]

This study aimed to determine the potential bidirectionality of the relationship between accelerometer-assessed between moderate-to-vigorous physical activity (MVPA), sedentary behaviour (SB), and frailty over time in older adults.

Spanish

ICFSR Task Force Perspective on Biomarkers for Sarcopenia and Frailty

L. Rodriguez-Mañas, I. Araujo de Carvalho, S. Bhasin,et al.

J Frailty Aging. 2020;9(1):4-8. doi: 10.14283/jfa.2019.32.

The International Conference on Frailty and Sarcopenia Research (ICFSR) Task Force - a group of academic and industry scientists from around the world -- met in February 2019 to discuss the current state of biomarker development for frailty and sarcopenia.

Spanish

Circulating Interleukin-6 Is Associated with Skeletal Muscle Strength, Quality, and Functional Adaptation with Exercise Training in Mobility-Limited Older Adults

G.J Grosicki, B.B. Barrett, D.A. Englund,et al.

J Frailty Aging. 2020;9(1):57-63. doi: 10.14283/jfa.2019.30.

The aim was to investigate relationships between circulating IL-6, skeletal muscle health and exercise adaptation in mobility-limited older adults.

Spanish

Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium

S. Bhasin, T.G. Travison, T.M. Maniniz, et al.

J Am Geriatr Soc. 2020 Mar 9. doi: 10.1111/jgs.16372. [Epub ahead of print]

The aim was to develop an evidence-based definition of sarcopenia that can facilitate identification of older adults at risk for clinically relevant outcomes (eg, self-reported mobility limitation, falls, fractures, and mortality), the Sarcopenia Definition and Outcomes Consortium (SDOC) crafted a set of position statements informed by a literature review and SDOC's analyses of eight epidemiologic studies, six randomized clinical trials, four cohort studies of special populations, and two nationally representative population-based studies.

Spanish

The Tilburg Frailty Indicator (TFI): New Evidence for Its Validity

R.J. Gobbens, P. Boersma, I. Uchmanowicz, et al.

Clin Interv Aging. 2020;15:265-274

The Tilburg Frailty Indicator (TFI) is a self-report user-friendly questionnaire for assessing multidimensional frailty among community-dwelling older people. The main aim of this study is to re-evaluate the validity of the TFI, both cross-sectionally and longitudinally, focusing on the predictive value of the total TFI and its physical, psychological, and social domains for adverse outcomes disability, indicators of healthcare utilization, and falls.

Spanish

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