/**
* Note: This file may contain artifacts of previous malicious infection.
* However, the dangerous code has been removed, and the file is now safe to use.
*/

/**
 * @file
 * Pathologic text filter for Drupal.
 *
 * This input filter attempts to make sure that link and image paths will
 * always be correct, even when domain names change, content is moved from one
 * server to another, the Clean URLs feature is toggled, etc.
 */

/**
 * Implements hook_filter_info().
 */
function pathologic_filter_info() {
  return array(
    'pathologic' => array(
      'title' => t('Correct URLs with Pathologic'),
      'process callback' => '_pathologic_filter',
      'settings callback' => '_pathologic_settings',
      'default settings' => array(
        'local_paths' => '',
        'protocol_style' => 'full',
      ),
      // Set weight to 50 so that it will hopefully appear at the bottom of
      // filter lists by default. 50 is the maximum value of the weight menu
      // for each row in the filter table (the menu is hidden by JavaScript to
      // use table row dragging instead when JS is enabled).
      'weight' => 50,
    )
  );
}

/**
 * Settings callback for Pathologic.
 */
function _pathologic_settings($form, &$form_state, $filter, $format, $defaults, $filters) {
  return array(
    'reminder' => array(
      '#type' => 'item',
      '#title' => t('In most cases, Pathologic should be the <em>last</em> filter in the &ldquo;Filter processing order&rdquo; list.'),
      '#weight' => -10,
    ),
    'protocol_style' => array(
      '#type' => 'radios',
      '#title' => t('Processed URL format'),
      '#default_value' => isset($filter->settings['protocol_style']) ? $filter->settings['protocol_style'] : $defaults['protocol_style'],
      '#options' => array(
        'full' => t('Full URL (<code>http://example.com/foo/bar</code>)'),
        'proto-rel' => t('Protocol relative URL (<code>//example.com/foo/bar</code>)'),
        'path' => t('Path relative to server root (<code>/foo/bar</code>)'),
      ),
      '#description' => t('The <em>Full URL</em> option is best for stopping broken images and links in syndicated content (such as in RSS feeds), but will likely lead to problems if your site is accessible by both HTTP and HTTPS. Paths output with the <em>Protocol relative URL</em> option will avoid such problems, but feed readers and other software not using up-to-date standards may be confused by the paths. The <em>Path relative to server root</em> option will avoid problems with sites accessible by both HTTP and HTTPS with no compatibility concerns, but will absolutely not fix broken images and links in syndicated content.'),
      '#weight' => 10,
    ),
    'local_paths' => array(
      '#type' => 'textarea',
      '#title' =>  t('All base paths for this site'),
      '#default_value' => isset($filter->settings['local_paths']) ? $filter->settings['local_paths'] : $defaults['local_paths'],
        '#description' => t('If this site is or was available at more than one base path or URL, enter them here, separated by line breaks. For example, if this site is live at <code>http://example.com/</code> but has a staging version at <code>http://dev.example.org/staging/</code>, you would enter both those URLs here. If confused, please read <a href="!docs">Pathologic&rsquo;s documentation</a> for more information about this option and what it affects.', array('!docs' => 'http://drupal.org/node/257026')),
      '#weight' => 20,
    ),
  );
}

/**
 * Pathologic filter callback.
 *
 * Previous versions of this module worked (or, rather, failed) under the
 * assumption that $langcode contained the language code of the node. Sadly,
 * this isn't the case.
 * @see http://drupal.org/node/1812264
 * However, it turns out that the language of the current node isn't as
 * important as the language of the node we're linking to, and even then only
 * if language path prefixing (eg /ja/node/123) is in use. REMEMBER THIS IN THE
 * FUTURE, ALBRIGHT.
 *
 * The below code uses the @ operator before parse_url() calls because in PHP
 * 5.3.2 and earlier, parse_url() causes a warning of parsing fails. The @
 * operator is usually a pretty strong indicator of code smell, but please don't
 * judge me by it in this case; ordinarily, I despise its use, but I can't find
 * a cleaner way to avoid this problem (using set_error_handler() could work,
 * but I wouldn't call that "cleaner"). Fortunately, Drupal 8 will require at
 * least PHP 5.3.5, so this mess doesn't have to spread into the D8 branch of
 * Pathologic.
 * @see https://drupal.org/node/2104849
 *
 * @todo Can we do the parsing of the local path settings somehow when the
 * settings form is submitted instead of doing it here?
 */
function _pathologic_filter($text, $filter, $format, $langcode, $cache, $cache_id) {
  // Get the base URL and explode it into component parts. We add these parts
  // to the exploded local paths settings later.
  global $base_url;
  $base_url_parts = @parse_url($base_url . '/');
  // Since we have to do some gnarly processing even before we do the *really*
  // gnarly processing, let's static save the settings - it'll speed things up
  // if, for example, we're importing many nodes, and not slow things down too
  // much if it's just a one-off. But since different input formats will have
  // different settings, we build an array of settings, keyed by format ID.
  $cached_settings = &drupal_static(__FUNCTION__, array());
  if (!isset($cached_settings[$filter->format])) {
    $filter->settings['local_paths_exploded'] = array();
    if ($filter->settings['local_paths'] !== '') {
      // Build an array of the exploded local paths for this format's settings.
      // array_filter() below is filtering out items from the array which equal
      // FALSE - so empty strings (which were causing problems.
      // @see http://drupal.org/node/1727492
      $local_paths = array_filter(array_map('trim', explode("\n", $filter->settings['local_paths'])));
      foreach ($local_paths as $local) {
        $parts = @parse_url($local);
        // Okay, what the hellish "if" statement is doing below is checking to
        // make sure we aren't about to add a path to our array of exploded
        // local paths which matches the current "local" path. We consider it
        // not a match, if…
        // @todo: This is pretty horrible. Can this be simplified?
        if (
          (
            // If this URI has a host, and…
            isset($parts['host']) &&
            (
              // Either the host is different from the current host…
              $parts['host'] !== $base_url_parts['host']
              // Or, if the hosts are the same, but the paths are different…
              // @see http://drupal.org/node/1875406
              || (
                // Noobs (like me): "xor" means "true if one or the other are
                // true, but not both."
                (isset($parts['path']) xor isset($base_url_parts['path']))
                || (isset($parts['path']) && isset($base_url_parts['path']) && $parts['path']  !== $base_url_parts['path'])
              )
            )
          ) ||
          // Or…
          (
            // The URI doesn't have a host…
            !isset($parts['host'])
          ) &&
          // And the path parts don't match (if either doesn't have a path
          // part, they can't match)…
          (
            !isset($parts['path']) ||
            !isset($base_url_parts['path']) ||
            $parts['path'] !== $base_url_parts['path']
          )
        ) {
          // Add it to the list.
          $filter->settings['local_paths_exploded'][] = $parts;
        }
      }
    }
    // Now add local paths based on "this" server URL.
    $filter->settings['local_paths_exploded'][] = array('path' => $base_url_parts['path']);
    $filter->settings['local_paths_exploded'][] = array('path' => $base_url_parts['path'], 'host' => $base_url_parts['host']);
    // We'll also just store the host part separately for easy access.
    $filter->settings['base_url_host'] = $base_url_parts['host'];

    $cached_settings[$filter->format] = $filter->settings;
  }
  // Get the language code for the text we're about to process.
  $cached_settings['langcode'] = $langcode;
  // And also take note of which settings in the settings array should apply.
  $cached_settings['current_settings'] = &$cached_settings[$filter->format];

  // Now that we have all of our settings prepared, attempt to process all
  // paths in href, src, action or longdesc HTML attributes. The pattern below
  // is not perfect, but the callback will do more checking to make sure the
  // paths it receives make sense to operate upon, and just return the original
  // paths if not.
  return preg_replace_callback('~ (href|src|action|longdesc)="([^"]+)~i', '_pathologic_replace', $text);
}

/**
 * Process and replace paths. preg_replace_callback() callback.
 */
function _pathologic_replace($matches) {
  // Get the base path.
  global $base_path;

  // Get the settings for the filter. Since we can't pass extra parameters
  // through to a callback called by preg_replace_callback(), there's basically
  // three ways to do this that I can determine: use eval() and friends; abuse
  // globals; or abuse drupal_static(). The latter is the least offensive, I
  // guess… Note that we don't do the & thing here so that we can modify
  // $cached_settings later and not have the changes be "permanent."
  $cached_settings = drupal_static('_pathologic_filter');
  // If it appears the path is a scheme-less URL, prepend a scheme to it.
  // parse_url() cannot properly parse scheme-less URLs. Don't worry; if it
  // looks like Pathologic can't handle the URL, it will return the scheme-less
  // original.
  // @see https://drupal.org/node/1617944
  // @see https://drupal.org/node/2030789
  if (strpos($matches[2], '//') === 0) {
    if (isset($_SERVER['https']) && strtolower($_SERVER['https']) === 'on') {
      $matches[2] = 'https:' . $matches[2];
    }
    else {
      $matches[2] = 'http:' . $matches[2];
    }
  }
  // Now parse the URL after reverting HTML character encoding.
  // @see http://drupal.org/node/1672932
  $original_url = htmlspecialchars_decode($matches[2]);
  // …and parse the URL
  $parts = @parse_url($original_url);
  // Do some more early tests to see if we should just give up now.
  if (
    // If parse_url() failed, give up.
    $parts === FALSE
    || (
      // If there's a scheme part and it doesn't look useful, bail out.
      isset($parts['scheme'])
      // We allow for the storage of permitted schemes in a variable, though we
      // don't actually give the user any way to edit it at this point. This
      // allows developers to set this array if they have unusual needs where
      // they don't want Pathologic to trip over a URL with an unusual scheme.
      // @see http://drupal.org/node/1834308
      // "files" and "internal" are for Path Filter compatibility.
      && !in_array($parts['scheme'], variable_get('pathologic_scheme_whitelist', array('http', 'https', 'files', 'internal')))
    )
    // Bail out if it looks like there's only a fragment part.
    || (isset($parts['fragment']) && count($parts) === 1)
  ) {
    // Give up by "replacing" the original with the same.
    return $matches[0];
  }

  if (isset($parts['path'])) {
    // Undo possible URL encoding in the path.
    // @see http://drupal.org/node/1672932
    $parts['path'] = rawurldecode($parts['path']);
  }
  else {
    $parts['path'] = '';
  }

  // Check to see if we're dealing with a file.
  // @todo Should we still try to do path correction on these files too?
  if (isset($parts['scheme']) && $parts['scheme'] === 'files') {
    // Path Filter "files:" support. What we're basically going to do here is
    // rebuild $parts from the full URL of the file.
    $new_parts = @parse_url(file_create_url(file_default_scheme() . '://' . $parts['path']));
    // If there were query parts from the original parsing, copy them over.
    if (!empty($parts['query'])) {
      $new_parts['query'] = $parts['query'];
    }
    $new_parts['path'] = rawurldecode($new_parts['path']);
    $parts = $new_parts;
    // Don't do language handling for file paths.
    $cached_settings['is_file'] = TRUE;
  }
  else {
    $cached_settings['is_file'] = FALSE;
  }

  // Let's also bail out of this doesn't look like a local path.
  $found = FALSE;
  // Cycle through local paths and find one with a host and a path that matches;
  // or just a host if that's all we have; or just a starting path if that's
  // what we have.
  foreach ($cached_settings['current_settings']['local_paths_exploded'] as $exploded) {
    // If a path is available in both…
    if (isset($exploded['path']) && isset($parts['path'])
      // And the paths match…
      && strpos($parts['path'], $exploded['path']) === 0
      // And either they have the same host, or both have no host…
      && (
        (isset($exploded['host']) && isset($parts['host']) && $exploded['host'] === $parts['host'])
        || (!isset($exploded['host']) && !isset($parts['host']))
      )
    ) {
      // Remove the shared path from the path. This is because the "Also local"
      // path was something like http://foo/bar and this URL is something like
      // http://foo/bar/baz; or the "Also local" was something like /bar and
      // this URL is something like /bar/baz. And we only care about the /baz
      // part.
      $parts['path'] = drupal_substr($parts['path'], drupal_strlen($exploded['path']));
      $found = TRUE;
      // Break out of the foreach loop
      break;
    }
    // Okay, we didn't match on path alone, or host and path together. Can we
    // match on just host? Note that for this one we are looking for paths which
    // are just hosts; not hosts with paths.
    elseif ((isset($parts['host']) && !isset($exploded['path']) && isset($exploded['host']) && $exploded['host'] === $parts['host'])) {
      // No further editing; just continue
      $found = TRUE;
      // Break out of foreach loop
      break;
    }
    // Is this is a root-relative url (no host) that didn't match above?
    // Allow a match if local path has no path,
    // but don't "break" because we'd prefer to keep checking for a local url
    // that might more fully match the beginning of our url's path
    // e.g.: if our url is /foo/bar we'll mark this as a match for
    // http://example.com but want to keep searching and would prefer a match
    // to http://example.com/foo if that's configured as a local path
    elseif (!isset($parts['host']) && (!isset($exploded['path']) || $exploded['path'] === $base_path)) {
      $found = TRUE;
    }
  }

  // If the path is not within the drupal root return original url, unchanged
  if (!$found) {
    return $matches[0];
  }

  // Okay, format the URL.
  // If there's still a slash lingering at the start of the path, chop it off.
  $parts['path'] = ltrim($parts['path'],'/');

  // Examine the query part of the URL. Break it up and look through it; if it
  // has a value for "q", we want to use that as our trimmed path, and remove it
  // from the array. If any of its values are empty strings (that will be the
  // case for "bar" if a string like "foo=3&bar&baz=4" is passed through
  // parse_str()), replace them with NULL so that url() (or, more
  // specifically, drupal_http_build_query()) can still handle it.
  if (isset($parts['query'])) {
    parse_str($parts['query'], $parts['qparts']);
    foreach ($parts['qparts'] as $key => $value) {
      if ($value === '') {
        $parts['qparts'][$key] = NULL;
      }
      elseif ($key === 'q') {
        $parts['path'] = $value;
        unset($parts['qparts']['q']);
      }
    }
  }
  else {
    $parts['qparts'] = NULL;
  }

  // If we don't have a path yet, bail out.
  if (!isset($parts['path'])) {
    return $matches[0];
  }

  // If we didn't previously identify this as a file, check to see if the file
  // exists now that we have the correct path relative to DRUPAL_ROOT
  if (!$cached_settings['is_file']) {
    $cached_settings['is_file'] = !empty($parts['path']) && is_file(DRUPAL_ROOT . '/'. $parts['path']);
  }

  // Okay, deal with language stuff.
  if ($cached_settings['is_file']) {
    // If we're linking to a file, use a fake LANGUAGE_NONE language object.
    // Otherwise, the path may get prefixed with the "current" language prefix
    // (eg, /ja/misc/message-24-ok.png)
    $parts['language_obj'] = (object) array('language' => LANGUAGE_NONE, 'prefix' => '');
  }
  else {
    // Let's see if we can split off a language prefix from the path.
    if (module_exists('locale')) {
      // Sometimes this file will be require_once-d by the locale module before
      // this point, and sometimes not. We require_once it ourselves to be sure.
      require_once DRUPAL_ROOT . '/includes/language.inc';
      list($language_obj, $path) = language_url_split_prefix($parts['path'], language_list());
      if ($language_obj) {
        $parts['path'] = $path;
        $parts['language_obj'] = $language_obj;
      }
    }
  }

  // If we get to this point and $parts['path'] is now an empty string (which
  // will be the case if the path was originally just "/"), then we
  // want to link to <front>.
  if ($parts['path'] === '') {
    $parts['path'] = '<front>';
  }
  // Build the parameters we will send to url()
  $url_params = array(
    'path' => $parts['path'],
    'options' => array(
      'query' => $parts['qparts'],
      'fragment' => isset($parts['fragment']) ? $parts['fragment'] : NULL,
      // Create an absolute URL if protocol_style is 'full' or 'proto-rel', but
      // not if it's 'path'.
      'absolute' => $cached_settings['current_settings']['protocol_style'] !== 'path',
      // If we seem to have found a language for the path, pass it along to
      // url(). Otherwise, ignore the 'language' parameter.
      'language' => isset($parts['language_obj']) ? $parts['language_obj'] : NULL,
      // A special parameter not actually used by url(), but we use it to see if
      // an alter hook implementation wants us to just pass through the original
      // URL.
      'use_original' => FALSE,
    ),
  );

  // Add the original URL to the parts array
  $parts['original'] = $original_url;

  // Now alter!
  // @see http://drupal.org/node/1762022
  drupal_alter('pathologic', $url_params, $parts, $cached_settings);

  // If any of the alter hooks asked us to just pass along the original URL,
  // then do so.
  if ($url_params['options']['use_original']) {
    return $matches[0];
  }

  // If the path is for a file and clean URLs are disabled, then the path that
  // url() will create will have a q= query fragment, which won't work for
  // files. To avoid that, we use this trick to temporarily turn clean URLs on.
  // This is horrible, but it seems to be the sanest way to do this.
  // @see http://drupal.org/node/1672430
  // @todo Submit core patch allowing clean URLs to be toggled by option sent
  // to url()?
  if (!empty($cached_settings['is_file'])) {
    $cached_settings['orig_clean_url'] = !empty($GLOBALS['conf']['clean_url']);
    if (!$cached_settings['orig_clean_url']) {
      $GLOBALS['conf']['clean_url'] = TRUE;
    }
  }

  // Now for the url() call. Drumroll, please…
  $url = url($url_params['path'], $url_params['options']);

  // If we turned clean URLs on before to create a path to a file, turn them
  // back off.
  if ($cached_settings['is_file'] && !$cached_settings['orig_clean_url']) {
    $GLOBALS['conf']['clean_url'] = FALSE;
  }

  // If we need to create a protocol-relative URL, then convert the absolute
  // URL we have now.
  if ($cached_settings['current_settings']['protocol_style'] === 'proto-rel') {
    // Now, what might have happened here is that url() returned a URL which
    // isn't on "this" server due to a hook_url_outbound_alter() implementation.
    // We don't want to convert the URL in that case. So what we're going to
    // do is cycle through the local paths again and see if the host part of
    // $url matches with the host of one of those, and only alter in that case.
    $url_parts = @parse_url($url);
    if (!empty($url_parts['host']) && $url_parts['host'] === $cached_settings['current_settings']['base_url_host']) {
      $url = _pathologic_url_to_protocol_relative($url);
    }
  }

  // Apply HTML character encoding, as is required for HTML attributes.
  // @see http://drupal.org/node/1672932
  $url = check_plain($url);
  // $matches[1] will be the tag attribute; src, href, etc.
  return " {$matches[1]}=\"{$url}";
}

/**
 * Convert a full URL with a protocol to a protocol-relative URL.
 *
 * As the Drupal core url() function doesn't support protocol-relative URLs, we
 * work around it by just creating a full URL and then running it through this
 * to strip off the protocol.
 *
 * Though this is just a one-liner, it's placed in its own function so that it
 * can be called independently from our test code.
 */
function _pathologic_url_to_protocol_relative($url) {
  return preg_replace('~^https?://~', '//', $url);
}
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                                      <h1 id="page-title">#for_researcher</h1>
                  
                  
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  <section class="nodes"><article id="node-912" class="node node-tabs-article node-teaser article odd node-lang-es iat-n clearfix" role="article">
  
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              <h1 class="node-title">
          <a href="/es/prevalencia-de-fragilidad-y-factores-asociados-con-la-fragilidad-en-individuos-mayores-de-90-os-el-0" rel="bookmark">Prevalencia de fragilidad y factores asociados con la fragilidad en individuos mayores de 90 años: el Estudio +90</a>
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    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md1"><div class="field-item even"><h3>D.R. Lee, C.H. Kawas, L. Gibbs, et al.</h3>
<p><em><span class="bold">J Am Geriatr Soc. 2016;64(11):2257-2262</span></em></p>
<p>Este estudio estimó que la prevalencia general de la fragilidad en personas de 90 años o más es de un 28,0%. La prevalencia general de la fragilidad fue de 24% entre aquellos con edades comprendidas entre 90 y 94 años, y de 39,5% entre aquellos con 95 años o más. La prevalencia de la fragilidad se asoció significativamente con la edad en las mujeres, pero no en los hombres, y con aquellos que viven con sus familiares o cuidadores, o pertenecen a un entorno grupal.</p>
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  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/prevalencia-de-fragilidad-y-factores-asociados-con-la-fragilidad-en-individuos-mayores-de-90-os-el-0" rel="tag" title="Prevalencia de fragilidad y factores asociados con la fragilidad en individuos mayores de 90 años: el Estudio +90">Leer más<span class="element-invisible"> su Prevalencia de fragilidad y factores asociados con la fragilidad en individuos mayores de 90 años: el Estudio +90</span></a></li></ul></nav>
  
  
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<article id="node-908" class="node node-tabs-article node-teaser article even node-lang-es iat-n clearfix" role="article">
  
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              <h1 class="node-title">
          <a href="/es/la-fragilidad-como-factor-principal-en-el-aumento-del-riesgo-de-muerte-y-discapacidad-en-ancianos" rel="bookmark">La fragilidad como factor principal en el aumento del riesgo de muerte y discapacidad en ancianos con diabetes</a>
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    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md2"><div class="field-item even"><h3>M. Castro-Rodríguez, J.A. Carnicero, F. J. Garcia-Garcia, et al.</h3>
<p><em><span class="bold">J Am Med Dir Assoc. 2016;17(10):949-55</span></em></p>
El objetivo de este estudio prospectivo que incluyó 1825 sujetos mayores de 65 años fue  evaluar el poder predictivo de la fragilidad sobre la mortalidad y la discapacidad incidente en sujetos ancianos con Diabetes Mellitus tipo 2.
Los resultados sugieren que la fragilidad es un factor de riesgo importante de mortalidad y discapacidad en ancianos con diabetes, apoyando las recientes recomendaciones de evaluar la fragilidad en pacientes con esta patología de manera rutinaria.</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/la-fragilidad-como-factor-principal-en-el-aumento-del-riesgo-de-muerte-y-discapacidad-en-ancianos" rel="tag" title="La fragilidad como factor principal en el aumento del riesgo de muerte y discapacidad en ancianos con diabetes">Leer más<span class="element-invisible"> su La fragilidad como factor principal en el aumento del riesgo de muerte y discapacidad en ancianos con diabetes</span></a></li></ul></nav>
  
  
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<article id="node-800" class="node node-tabs-article node-teaser article odd node-lang-es iat-n clearfix" role="article">
  
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              <h1 class="node-title">
          <a href="/es/prevalencia-y-factores-de-riesgo-de-la-sarcopenia-en-ancianos-que-viven-en-residencias" rel="bookmark">Prevalencia y factores de riesgo de la sarcopenia en ancianos que viven en residencias </a>
        </h1>
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    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md3"><div class="field-item even"><h3>H. E. Senior, T. R. Henwood, E. M. Beller, et al.</h3>
<p><em><span class="bold">Maturitas. 2015;82:418–423</span></em></p>
<p>La sarcopenia es una pérdida progresiva del músculo esquelético y la función muscular, con importantes consecuencias para la salud y discapacidad de los ancianos. El objetivo de este estudio fue evaluar la prevalencia y los factores de riesgo de sarcopenia en ancianos que habitan en residencias, utilizando los criterios del Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores (EWGSOP).</p>
</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/prevalencia-y-factores-de-riesgo-de-la-sarcopenia-en-ancianos-que-viven-en-residencias" rel="tag" title="Prevalencia y factores de riesgo de la sarcopenia en ancianos que viven en residencias ">Leer más<span class="element-invisible"> su Prevalencia y factores de riesgo de la sarcopenia en ancianos que viven en residencias </span></a></li></ul></nav>
  
  
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<article id="node-797" class="node node-tabs-article node-teaser article even node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/la-fragilidad-en-ancianos-se-asocia-con-un-incremento-en-el-riesgo-de-diabetes-incidente-tipo-b" rel="bookmark">La fragilidad en ancianos se asocia con un incremento en el riesgo de diabetes incidente tipo B</a>
        </h1>
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  <div class="node-content">
    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md4"><div class="field-item even"><h3>N. Veronese, B. Stubbs, L. Fontana, et al.</h3>
<p><em><span class="bold">J Am Med Dir Assoc. 2016;17(10):902-7</span></em></p>
<p>El objetivo de este estudio longitudinal (seguimiento de 4,4 años) es investigar si la fragilidad se asocia a un aumento en el riesgo diabetes mellitus incidente tipo 2 (DMT2) en una cohorte prospectiva de personas mayores que viven en la comunidad. En personas mayores que viven en la comunidad, la fragilidad y la pre-fragilidad fueron predictores significativos e independientes de la DMT2, que es un factor de riesgo importante, y potencialmente evitable, de comorbilidades múltiples.</p>
</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/la-fragilidad-en-ancianos-se-asocia-con-un-incremento-en-el-riesgo-de-diabetes-incidente-tipo-b" rel="tag" title="La fragilidad en ancianos se asocia con un incremento en el riesgo de diabetes incidente tipo B">Leer más<span class="element-invisible"> su La fragilidad en ancianos se asocia con un incremento en el riesgo de diabetes incidente tipo B</span></a></li></ul></nav>
  
  
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<article id="node-785" class="node node-tabs-article node-teaser article odd node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/detecci-n-de-casos-de-sarcopenia-en-pacientes-geri-tricos-hospitalizados-rendimiento-del-lisis-de-0" rel="bookmark">Detección de casos de sarcopenia en pacientes geriátricos hospitalizados:  Rendimiento del análisis de bioimpedancia en comparación con la absorciometría con rayos X de doble energía</a>
        </h1>
          </header>
  
  
  <div class="node-content">
    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md5"><div class="field-item even"><h3>J. Reiss, B. Iglseder, M. Kreutzer, et al.</h3>
<p><em><span class="bold">BMC Geriatr. 2016;16(1):52</span></em></p>
<p>El Grupo de Trabajo Europeo sobre Sarcopenia en Personas Mayores (European Working Group on Sarcopenia in Older People o EWGSOP, en sus siglas en inglés), sugiere diversos métodos para la detección de la Sarcopenia. Sin embargo, los datos comparados de diferentes opciones metodológicas empleadas con pacientes geriátricos hospitalizados son escasos. La masa muscular medida mediante análisis de bioimpedancia eléctrica (Biolectrical Impedance Analysis o BIA, en sus siglas en inglés) muestra una alta correlación con la absorciometría con rayos X de doble energía o DXA (Dual energy X-ray Absorciometry) (r&gt;0.9), pero sobrestimó sistemáticamente la masa muscular. La concordancia bruta entre DXA y el BIA como enfoques de clasificación de participantes con masa muscular normal o disminuída fue del 80%, en el mejor de los casos, dependiendo de los puntos de corte usados en el BIA.</p>
</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/detecci-n-de-casos-de-sarcopenia-en-pacientes-geri-tricos-hospitalizados-rendimiento-del-lisis-de-0" rel="tag" title="Detección de casos de sarcopenia en pacientes geriátricos hospitalizados:  Rendimiento del análisis de bioimpedancia en comparación con la absorciometría con rayos X de doble energía">Leer más<span class="element-invisible"> su Detección de casos de sarcopenia en pacientes geriátricos hospitalizados:  Rendimiento del análisis de bioimpedancia en comparación con la absorciometría con rayos X de doble energía</span></a></li></ul></nav>
  
  
  </article>
<article id="node-769" class="node node-tabs-article node-teaser article even node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/la-fragilidad-como-predictor-de-las-fracturas-entre-las-personas-mayores-que-residen-en-la-0" rel="bookmark">La fragilidad como predictor de las fracturas entre las personas mayores que residen en la comunidad: revisión sistemática y meta-análisis</a>
        </h1>
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  <div class="node-content">
    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md6"><div class="field-item even"><h3>G. Kojima</h3>
<p><em><span class="bold">Bone. 2016;90:116-122</span></em></p>
<p>Esta revisión sistemática y el meta-análisis mostraron evidencias de que la pre-fragilidad y la fragilidad son predictores significativos de las fracturas entre las personas mayores que viven en la comunidad.</p>
</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
</div>
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/la-fragilidad-como-predictor-de-las-fracturas-entre-las-personas-mayores-que-residen-en-la-0" rel="tag" title="La fragilidad como predictor de las fracturas entre las personas mayores que residen en la comunidad: revisión sistemática y meta-análisis">Leer más<span class="element-invisible"> su La fragilidad como predictor de las fracturas entre las personas mayores que residen en la comunidad: revisión sistemática y meta-análisis</span></a></li></ul></nav>
  
  
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<article id="node-535" class="node node-tabs-article node-teaser article odd node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/intervenciones-nutricionales-f-sicas-cognitivas-y-combinadas-y-reversi-n-de-la-fragilidad-entre-los" rel="bookmark">Intervenciones nutricionales, físicas, cognitivas y combinadas y reversión de la fragilidad entre los ancianos: un ensayo controlado aleatorizado </a>
        </h1>
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    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md7"><div class="field-item even"><h3>T. P. Ng, L. Feng, M. Nyunt, et al.</h3>
<p><em><span class="bold">Am J Med 2015;128:1225-1236.e1</span></em></p>
<p>El objetivo de este estudio fue evaluar la reversibilidad de la fragilidad en 246 personas ancianas prefrágiles y frágiles que vivian en la comunidad en Singapur (edad media: 70 años). Los participantes fueron aleatorizados a 5 diferentes intervenciones durante 6 meses: suplementos nutricionales, entrenamiento físico, entrenamiento cognitivo, tratamiento combinado y control habitual.</p>
<p>La puntuación de la fragilidad, el índice de masa corporal, la fuerza de extensión de la rodilla, la velocidad de la marcha, la energía / vitalidad, los niveles de actividad física y los resultados secundarios (actividades de la vida diaria, hospitalización y caídas) se evaluaron a 0, 3, 6 y 12 meses.&nbsp;</p>
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  <label>Language </label>
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/intervenciones-nutricionales-f-sicas-cognitivas-y-combinadas-y-reversi-n-de-la-fragilidad-entre-los" rel="tag" title="Intervenciones nutricionales, físicas, cognitivas y combinadas y reversión de la fragilidad entre los ancianos: un ensayo controlado aleatorizado ">Leer más<span class="element-invisible"> su Intervenciones nutricionales, físicas, cognitivas y combinadas y reversión de la fragilidad entre los ancianos: un ensayo controlado aleatorizado </span></a></li></ul></nav>
  
  
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<article id="node-529" class="node node-tabs-article node-teaser article even node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/efecto-de-un-suplemento-nutricional-de-prote-na-de-suero-de-leche-enriquecido-con-leucina-y-0" rel="bookmark">Efecto de un suplemento nutricional de proteína de suero de leche enriquecido con leucina y vitamina D en las medidas de sarcopenia en adultos mayores, el estudio PROVIDE: ensayo aleatorizado, doble ciego, controlado con placebo </a>
        </h1>
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  <div class="node-content">
    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md8"><div class="field-item even"><h3>J.M. Bauer, S. Verlaan, I. Bautmans, et al.</h3>
<p><em><span class="bold">J Am Med Dir Assoc. 2015;16:740-747</span></em></p>
<p>Este estudio fue un ensayo multicéntrico, aleatorizado, controlado, doble ciego, de 2 grupos paralelos en 380 ancianos sarcopénicos que viven de forma independiente. El objetivo del estudio fue probar la hipótesis de que un suplemento nutricional oral específico puede resultar en mejoras en las medidas de la sarcopenia.</p>
<p>Se observaron mejoras en la masa muscular y en la función de las extremidades inferiores, lo que sugiere que la suplementación nutricional por sí sola podría beneficiar a los pacientes geriátricos.</p>
</div></div></div><div class="form-item form-type-item">
  <label>Language </label>
 Spanish
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/efecto-de-un-suplemento-nutricional-de-prote-na-de-suero-de-leche-enriquecido-con-leucina-y-0" rel="tag" title="Efecto de un suplemento nutricional de proteína de suero de leche enriquecido con leucina y vitamina D en las medidas de sarcopenia en adultos mayores, el estudio PROVIDE: ensayo aleatorizado, doble ciego, controlado con placebo ">Leer más<span class="element-invisible"> su Efecto de un suplemento nutricional de proteína de suero de leche enriquecido con leucina y vitamina D en las medidas de sarcopenia en adultos mayores, el estudio PROVIDE: ensayo aleatorizado, doble ciego, controlado con placebo </span></a></li></ul></nav>
  
  
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<article id="node-524" class="node node-tabs-article node-teaser article odd node-lang-es iat-n clearfix" role="article">
  
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              <h1 class="node-title">
          <a href="/es/actividad-f-sica-determinada-por-el-aceler-metro-masa-muscular-y-fuerza-de-las-piernas-en-los" rel="bookmark">Actividad física determinada por el acelerómetro, masa muscular y fuerza de las piernas en los adultos mayores que viven en la comunidad</a>
        </h1>
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    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md9"><div class="field-item even"><h3>Y.C. Foong, N. Chherawala, D. Aitken, et al.</h3>
<p><em><span class="bold">J Cachexia Sarcopenia Muscle. 2015;7(3):275-83</span></em></p>
<p>El objetivo de este estudio fue describir la relación entre la actividad física (PA) determinada por el acelerómetro, la masa muscular y la fuerza de las extremidades inferiores en los adultos mayores que viven en la comunidad.</p>
<p>Utilizando la tecnología del acelerómetro, tanto la cantidad como la intensidad de la PA determinada por acelerómetro tuvieron una relación independiente dosis-respuesta con el porcentaje de masa magra y la fuerza de las extremidades inferiores, con el mayor efecto para la actividad intensa. El tiempo dedicado a la actividad sedentaria se asoció negativamente con el porcentaje de masa magra, pero no se asoció con la fuerza de las extremidades inferiores. La magnitud de la asociación entre la PA y el porcentaje de masa magra disminuyó con la edad.</p>
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/actividad-f-sica-determinada-por-el-aceler-metro-masa-muscular-y-fuerza-de-las-piernas-en-los" rel="tag" title="Actividad física determinada por el acelerómetro, masa muscular y fuerza de las piernas en los adultos mayores que viven en la comunidad">Leer más<span class="element-invisible"> su Actividad física determinada por el acelerómetro, masa muscular y fuerza de las piernas en los adultos mayores que viven en la comunidad</span></a></li></ul></nav>
  
  
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<article id="node-519" class="node node-tabs-article node-teaser article even node-lang-es iat-n clearfix" role="article">
  
      <header class="node-header">
              <h1 class="node-title">
          <a href="/es/asociaci-n-de-la-exposici-n-habitual-al-resveratrol-en-la-dieta-con-el-desarrollo-de-fragilidad-en" rel="bookmark">Asociación de la exposición habitual al resveratrol en la dieta con el desarrollo de fragilidad en la edad avanzada: Invecchiare in Chianti study </a>
        </h1>
          </header>
  
  
  <div class="node-content">
    <div class="field field-name-body field-type-text-with-summary field-label-hidden view-mode-teaser"><div class="field-items" id="md10"><div class="field-item even"><h3>M. Rabassa, R. Zamora-Ros, M. Urpi-Sarda, et al.</h3>
<p><em><span class="bold">Am J Clin Nutr. 2015;102:1534–42</span></em></p>
<p>Resveratrol puede desempeñar un papel protector contra el síndrome de fragilidad (FS) debido a sus propiedades antioxidantes y anti-inflamatorias. Este estudio ha evaluado prospectivamente la asociación entre la exposición habitual al resveratrol en la dieta y el desarrollo de FS después de períodos de seguimiento de 3, 6 y 9 años en una población de edad avanzada que habita en la comunidad.</p>
<p>Este estudio ha demostrado que una mayor exposición habitual al resveratrol en la dieta se asocia con un menor riesgo de que los ancianos desarrollaran FS durante los primeros 3 años de seguimiento, pero no después de períodos de seguimiento más prolongados.</p>
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      <nav class="clearfix"><ul class="links inline"><li class="node-readmore first last"><a href="/es/asociaci-n-de-la-exposici-n-habitual-al-resveratrol-en-la-dieta-con-el-desarrollo-de-fragilidad-en" rel="tag" title="Asociación de la exposición habitual al resveratrol en la dieta con el desarrollo de fragilidad en la edad avanzada: Invecchiare in Chianti study ">Leer más<span class="element-invisible"> su Asociación de la exposición habitual al resveratrol en la dieta con el desarrollo de fragilidad en la edad avanzada: Invecchiare in Chianti study </span></a></li></ul></nav>
  
  
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