#for_researcher

The Martin Vigorimeter Represents a Reliable and More Practical Tool Than the Jamar Dynamometer to Assess Handgrip Strength in the Geriatric Patient

W.M. Sipers, L.B. Verdijk, S.J. Sipers, et al.

J Am Med Dir Assoc. 2016;17(5):466

The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.

 

Spanish

Measurements of skeletal muscle mass and power are positively related to a Mediterranean dietary pattern in women

E. Kelaiditi, A. Jennings, C.J. Steves, et al.

Osteoporos Int. 2016;27(11):3251-3260

The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.

 

Spanish

Use of the frailty index in evaluating the prognosis of older people in Beijing: A cohort study with an 8-year follow-up

L. Ma, L. Zhang, Z. Tang, et al.

Arch Gerontol Geriatr. 2016 ;64:172-7

The present study aimed to evaluate the prevalence of frailty and determine if the frailty index, a comprehensive geriatric assessment, was associated with the prognosis of older people in a Chinese population.

Results obtained suggests that the frailty index increases with age, and may be a significant tool for evaluation of the prognosis of older people in China.

 

Spanish

Sarcopenia Is Associated With Lower Skeletal Muscle Capillarization and Exercise Capacity in Older Adults

S.J. Prior, A.S. Ryan, J.B. Blumenthal, et al.

J Gerontol A Biol Sci Med Sci. 2016;71(8):1096-101

In this study was tested the hypothesis that skeletal muscle capillarization and exercise capacity (VO2max) are lower in sarcopenic than in nonsarcopenic older adults and that the degree of sarcopenia is related to lower skeletal muscle capillarization.

Results obtained suggest that low skeletal muscle capillarization is one factor that may contribute to sarcopenia and reduced exercise capacity in older adults by limiting diffusion of substrates, oxygen, hormones, and nutrients.

 

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Computed tomography abbreviated assessment of sarcopenia following trauma: The CAAST measurement predicts 6-month mortality in older adult trauma patients

C.M. Leeper, E. Lin, M. Hoffman, et al.

J Trauma Acute Care Surg. 2016;80(5):805-11

Older adult trauma patients are at increased risk of poor outcome, both immediately after injury and beyond hospital discharge. Identifying patients early in the hospital stay who are at increased risk of death after discharge can be challenging.

Results suggest that sarcopenia is a strong predictor of 6-month postdischarge mortality for older adults. The CAAST measurement is an efficient and inexpensive measure that can allow clinicians to target older trauma patients at risk of poor outcome for early intervention and/or palliative care services.

 

Spanish

Polypharmacy as a Risk Factor for Clinically Relevant Sarcopenia: Results From the Berlin Aging Study II

M. König, D. Spira, I. Demuth, et al.

J Gerontol A Biol Sci Med Sci. 2017;73(1):117-122

This study have shown an independent association between polypharmacy and clinically relevant sarcopenia, based on the ALM/BMI-cutoffs defined by the FNIH sarcopenia project.

 

Spanish

Depression and frailty in later life: a systematic review

L. Vaughan, A.L. Corbin, J.S. Goveas

Clin Interv Aging. 2015;10:1947-58

Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced old age. This review examined the published literature on cross-sectional and longitudinal associations between frailty and depressive symptomatology.

Prospective relationship between depressive symptomatology and increased risk of incident frailty was robust, while the opposite relationship was less conclusive. The presence of comorbidities that interact with depressive symptomatology increased incident frailty risk.

 

Spanish

Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: A case-control study

S. Verlaan, T.J. Aspray, J.M. Bauer, et al.

Clin Nutr. 2017; 36(1):267-274

The aim of this study was to compare functional and nutritional status, body composition, and quality of life of older adults between age and sex-matched older adults with and without sarcopenia.

In non-malnourished older adults with and without sarcopenia, it was observed that sarcopenia substantially impacted self-reported quality of life and physical activity levels. Differences in nutrient concentrations and dietary intakes were identified, which might be related to the differences in muscle mass, strength and function between the two groups.

 

Spanish

C-reactive protein, frailty and overnight hospital admission in elderly individuals: A population-based study

Y. Zhu, Z. Liu, Y. Wang, et al.

Arch Gerontol Geriatr. 2016;64:1-5

C-reactive protein (CRP), an important inflammatory biomarker, has been linked to various diseases (e.g., cardiovascular disease). This paper aimed to investigate the associations of high sensitivity C-reactive protein (hsCRP) with frailty and overnight hospital admission in an elderly Chinese population.

Authors concluded that elevated levels of hsCRP were associated with increased risks of frailty and overnight hospital admission among elderly individuals in Rugao.

 

Spanish

Serum levels of C-terminal agrin fragment (CAF) are associated with sarcopenia in older multimorbid community-dwellers: Results from the ilSIRENTE study

F. Landi, R. Calvani, M. Lorenzi, et al.

Exp Gerontol. 2016;79:31-36

The C-terminal agrin fragment (CAF) is a circulating byproduct of neuromuscular junction disassembly. The present study was undertaken to verify if serum CAF levels were associated with sarcopenia in a population of old and very old persons living in the community.

The obtained results suggest that elevated serum CAF levels are associated with sarcopenia, independent of age, gender and several clinical, functional, anthropometric, and biochemical variables.

 

Spanish

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