Par investigadores
M. König, D. Spira, I. Demuth, et al.J Gerontol A Biol Sci Med Sci. 2017;73(1):117-122 This study have shown an independent association between polypharmacy and clinically relevant sarcopenia, based on the ALM/BMI-cutoffs defined by the FNIH sarcopenia project.
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L. Vaughan, A.L. Corbin, J.S. GoveasClin Interv Aging. 2015;10:1947-58 Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced old age. This review examined the published literature on cross-sectional and longitudinal associations between frailty and depressive symptomatology. Prospective relationship between depressive symptomatology and increased risk of incident frailty was robust, while the opposite relationship was less conclusive. The presence of comorbidities that interact with depressive symptomatology increased incident frailty risk.
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S. Verlaan, T.J. Aspray, J.M. Bauer, et al.Clin Nutr. 2017; 36(1):267-274 The aim of this study was to compare functional and nutritional status, body composition, and quality of life of older adults between age and sex-matched older adults with and without sarcopenia. In non-malnourished older adults with and without sarcopenia, it was observed that sarcopenia substantially impacted self-reported quality of life and physical activity levels. Differences in nutrient concentrations and dietary intakes were identified, which might be related to the differences in muscle mass, strength and function between the two groups.
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Y. Zhu, Z. Liu, Y. Wang, et al.Arch Gerontol Geriatr. 2016;64:1-5 C-reactive protein (CRP), an important inflammatory biomarker, has been linked to various diseases (e.g., cardiovascular disease). This paper aimed to investigate the associations of high sensitivity C-reactive protein (hsCRP) with frailty and overnight hospital admission in an elderly Chinese population. Authors concluded that elevated levels of hsCRP were associated with increased risks of frailty and overnight hospital admission among elderly individuals in Rugao.
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F. Landi, R. Calvani, M. Lorenzi, et al.Exp Gerontol. 2016;79:31-36 The C-terminal agrin fragment (CAF) is a circulating byproduct of neuromuscular junction disassembly. The present study was undertaken to verify if serum CAF levels were associated with sarcopenia in a population of old and very old persons living in the community. The obtained results suggest that elevated serum CAF levels are associated with sarcopenia, independent of age, gender and several clinical, functional, anthropometric, and biochemical variables.
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Y. Yoshimura, H. Wakabayashi, M. Yamada, et al.J Am Med Dir Assoc. 2017; 18(6):553.e1-553.e16 This systematic review and meta-analysis showed some positive effects of exercise and nutritional interventions for treating sarcopenia in older people.
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