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P. Lopez, R.S. Pinto, R. Radaelli, et al.Aging Clin Exp Res. 2017 Nov 29. doi: 10.1007/s40520-017-0863-z. [Epub ahead of print] Exercise is one of the most important components in frailty prevention and treatment. Therefore, we systematically reviewed the effect of resistance training (RT) alone or combined with multimodal exercise intervention on muscle hypertrophy, maximal strength, power output, functional performance, and falls incidence in physically frail elderly.
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W.M. Sipers, L.B. Verdijk, S.J. Sipers, et al.J Am Med Dir Assoc. 2016;17(5):466 The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.
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E. Kelaiditi, A. Jennings, C.J. Steves, et al.Osteoporos Int. 2016;27(11):3251-3260 The loss of skeletal muscle mass, strength, and function with age are contributing risk factors for the onset of sarcopenia, frailty, osteoporosis, fractures, and mortality. For the first time in a northern European population, it has been observed a significant positive association between the Mediterranean diet score and FFM% (fat-free mass / weight × 100) and leg explosive power (LEP, watts/kg) in healthy women that are potentially clinically relevant, independent of the factors known to influence muscle outcomes. These findings emphasize the potential role for overall diet quality based on the Mediterranean diet in the prevention of age-related loss of skeletal muscle outcomes.
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L. Ma, L. Zhang, Z. Tang, et al.Arch Gerontol Geriatr. 2016 ;64:172-7 The present study aimed to evaluate the prevalence of frailty and determine if the frailty index, a comprehensive geriatric assessment, was associated with the prognosis of older people in a Chinese population. Results obtained suggests that the frailty index increases with age, and may be a significant tool for evaluation of the prognosis of older people in China.
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S.J. Prior, A.S. Ryan, J.B. Blumenthal, et al.J Gerontol A Biol Sci Med Sci. 2016;71(8):1096-101 In this study was tested the hypothesis that skeletal muscle capillarization and exercise capacity (VO2max) are lower in sarcopenic than in nonsarcopenic older adults and that the degree of sarcopenia is related to lower skeletal muscle capillarization. Results obtained suggest that low skeletal muscle capillarization is one factor that may contribute to sarcopenia and reduced exercise capacity in older adults by limiting diffusion of substrates, oxygen, hormones, and nutrients.
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C.M. Leeper, E. Lin, M. Hoffman, et al.J Trauma Acute Care Surg. 2016;80(5):805-11 Older adult trauma patients are at increased risk of poor outcome, both immediately after injury and beyond hospital discharge. Identifying patients early in the hospital stay who are at increased risk of death after discharge can be challenging. Results suggest that sarcopenia is a strong predictor of 6-month postdischarge mortality for older adults. The CAAST measurement is an efficient and inexpensive measure that can allow clinicians to target older trauma patients at risk of poor outcome for early intervention and/or palliative care services.
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