For Researchers
E. Marzetti, A. Picca, F. Marini, et al.Exp Gerontol. 2019;122:129-138 This study was designed to explore the association between a large panel of inflammatory biomolecules and physical frailty and sarcopenia in older adults through a multivariate statistical approach. Gender-specific inflammatory patterns were also explored. |
L. Munguia, I. Rubio-Gayosso, I. Ramirez-Sanchez, et al.J Gerontol A Biol Sci Med Sci. 2019 May 6. pii: glz107. doi: 10.1093/gerona/glz107. [Epub ahead of print] The age-related decline in mass, strength and performance of skeletal muscle is associated with loss of independence, falls risk, disability, institutionalization and death. To determine whether a cocoa supplement enriched in flavonoids can improve plasma markers of oxidative stress and inflammation, physical performance and frailty in middle and older age subjects, we conducted a two-phase, randomized, double blind, clinical trial. |
A. Granic, N. Mendonça, A.A. Sayer, et al.Clin Nutr. 2019 Jan 21. pii: S0261-5614(19)30011-1. doi: 10.1016/j.clnu.2019.01.009. [Epub ahead of print] The aim was to investigate the association between healthy dietary patterns DPs and the risk of sarcopenia over 3 years, and to determine whether protein intake influences this relationship in community-dwelling older adults from the Newcastle 85 + Study. |
M. Isanejad, J. Sirola, T. Rikkonen, et al.Eur J Nutr. 2019 May 7. doi: 10.1007/s00394-019-01978-7. [Epub ahead of print] Nordic nutrition recommendations (2012) suggest protein intake ≥ 1.1 g/kg body weight (BW) to preserve physical function in Nordic older adults. However, no published study has used this cut-off to evaluate the association between protein intake and frailty. This study examined associations between protein intake, and sources of protein intake, with frailty status at the 3-year follow-up. |
M. Karlsson, W. Becker, K. Michaëlsson, et al.Clin Nutr. 2019 Apr 18. pii: S0261-5614(19)30182-7. doi: 10.1016/j.clnu.2019.04.009. [Epub ahead of print] The growing recognition of the significance of sarcopenia has highlighted the need to understand etiologic factors, where food intake likely plays a role. The aim was to investigate the association between dietary patterns at mean age 71 and the prevalence of sarcopenia at mean age 87 in a Swedish cohort of community dwelling men. |
K. Liberman, R. Njemini, Y. Luiking, et al.Aging Clin Exp Res. 2019 May 2. doi: 10.1007/s40520-019-01208-4. [Epub ahead of print] A chronic low-grade inflammatory profile (CLIP) is associated with sarcopenia in older adults. Protein and Vitamin (Vit)D have immune-modulatory potential, but evidence for effects of nutritional supplementation on CLIP is limited. The aim was to investigate whether 13 weeks of nutritional supplementation of VitD and leucine-enriched whey protein affected CLIP in subjects enrolled in the PROVIDE-study, as a secondary analysis. |



