For Healthcare Providers
N .Veronese, B. Stubbs, L. Punzi, et al.Ageing Res Rev. 2019;51:48-54 Malnutrition plays a role in the development of poor physical performance, frailty and sarcopenia. The use of nutritional supplementations for improving physical performance and muscle strength parameters in older people is unclear. We therefore aimed to summarize the effect of nutritional supplementations compared to placebo on physical performance (i.e. tests more investigating physical function, utilising aerobic capacity & muscle power) and muscle strength (i.e. tests depending on muscle power) outcomes in older people in randomized controlled trials (RCTs). |
K. Liberman, R. Njemini, Y. Luiking, et al.Aging Clin Exp Res. 2019 May 2. doi: 10.1007/s40520-019-01208-4. [Epub ahead of print] A chronic low-grade inflammatory profile (CLIP) is associated with sarcopenia in older adults. Protein and Vitamin (Vit)D have immune-modulatory potential, but evidence for effects of nutritional supplementation on CLIP is limited. The aim was to investigate whether 13 weeks of nutritional supplementation of VitD and leucine-enriched whey protein affected CLIP in subjects enrolled in the PROVIDE-study, as a secondary analysis. |
S.S.Y. Yeung, E.M. Reijniers, V.K. Pham, et al.J Cachexia Sarcopenia Muscle. 2019 Apr 16. doi: 10.1002/jcsm.12411. [Epub ahead of print] Sarcopenia is a potentially modifiable risk factor for falls and fractures in older adults, but the strength of the association between sarcopenia, falls, and fractures is unclear. This study aims to systematically assess the literature and perform a meta-analysis of the association between sarcopenia with falls and fractures among older adults. |
M.A. Perez-Sousa, L.C. Venegas-Sanabria, D.A. Chavarro-Carvajal, et al.J Cachexia Sarcopenia Muscle. 2019 May 8. doi: 10.1002/jcsm.12444. [Epub ahead of print] Sarcopenia in older adults is strongly associated with an increase in dependency in activities of daily living (ADL) and with a decline in gait speed. Interestingly, gait speed has been shown to independently predict mortality. In this context, our study aimed to explore the mediator role of gait speed on the relationship between sarcopenia and dependency in ADL. |
D. Spira, N. Buchmann, M. König, et al.Nutrition. 2019;62:1-6 Sex-specific differences in factors associated with aging and lifespan, such as sarcopenia and disease development, are increasingly recognized. The study aims to assess sex-specific aspects of the association between vitamin D insufficiency and low lean mass as well as between vitamin D insufficiency and the frailty phenotype. |
M. Bernabeu-Wittel, Á. González-Molina, R. Fernández-Ojeda, et al.J Clin Med. 2019 Apr 18;8(4). pii: E535. doi: 10.3390/jcm8040535. We performed a multicenter prospective observational study in six hospitals in order to assess prevalence, clinical features, outcome and associated risk factors of sarcopenia and frailty in a hospital-based population of polypathological patients. |