For Healthcare Providers
M. Tosato, E. Marzetti, M. Cesari, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT The aim of this article is to critically review available methods for muscle mass estimation, highlighting strengths and weaknesses of each of them as well as their proposed field of application. |
E. Marzetti, R. Calvani, M. Tosato, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” project (the SPRINTT project) has operationalized a specific condition, named physical frailty and sarcopenia (PF&S), characterized by the combination of low physical performance (based on the Short Physical Performance Battery) and low muscle mass (according to the FNIH cut-points). A randomized controlled trial will be conducted to evaluate the efficacy of a multi-component intervention for preventing mobility disability and other adverse health outcomes in older adults with PF&S. |
E. Marzetti, R. Calvani, M. Tosato, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT The present review summarizes the available evidence in support of physical activity as a remedy against physical frailty and sarcopenia. |
R. Le Lain, C. Ignaszewski, I. Klingmann, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT The present article describes the SPRINTT workpackage activities aimed at engaging the scientific discussion on the physical frailty and sarcopenia with the EMA as one of its interlocutor acknowledging the need to collaborate on this topic to foster a productive dialogue. |
R. Bernabei, L. Mariotti, P. Bordes, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT The “Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies” (SPRINTT) project has been designed to produce significant advancements in the management of older persons with PF&S. |
R. Calvani, F. Marini, M. Cesari, et al.Aging Clin Exp Res Epub 2017 Feb 10 CLICK HERE TO READ THE FULL TEXT This review provides an overview of currently available biological markers for PF and sarcopenia, as well as a critical appraisal of strengths and weaknesses of traditional procedures for biomarker development in the field. A novel approach for biomarker identification and validation, based on multivariate methodologies, is also discussed.
|



