For Healthcare Providers

Frailty as a predictor of fractures among community-dwelling older people: A systematic review and meta-analysis

G. Kojima

Bone. 2016;90:116-122

This systematic review and meta-analysis showed evidence that pre-frailty and frailty are significant predictors of fractures among community-dwelling older people.

Emergency general surgery specific frailty index: A validation study

T.O. Jokar, K. Ibraheem, P. Rhee, et al.

J Trauma Acute Care Surg. 2016;81(2):254-60

Assessment of operative risk in geriatric patients undergoing emergency general surgery (EGS) is challenging. Frailty is an established measure for risk assessment in surgical cases. The aim of our study was to validate a modified 15 variable emergency general surgery specific frailty index (EGSFI). Data obtained suggest that the 15-variable validated EGSFI is a simple and reliable bedside tool to determine the frailty status of patients undergoing emergency general surgery.

C-reactive protein, frailty and overnight hospital admission in elderly individuals: A population-based study

Y. Zhu, Z. Liu, Y. Wang, et al.

Arch Gerontol Geriatr. 2016;64:1-5

C-reactive protein (CRP), an important inflammatory biomarker, has been linked to various diseases (e.g., cardiovascular disease). This paper aimed to investigate the associations of high sensitivity C-reactive protein (hsCRP) with frailty and overnight hospital admission in an elderly Chinese population.

Authors concluded that elevated levels of hsCRP were associated with increased risks of frailty and overnight hospital admission among elderly individuals in Rugao.

Serum markers of inflammation and oxidative stress in sarcopenia

B. Can, O. Kara, M.C. Kizilarslanoglu, et al.

Aging Clin Exp Res. 2017;29(4):745-752

The aim of the study was to evaluate the relationship between sarcopenia and biomarkers that may be involved in its pathogenesis and hence allow early detection. The present study demonstrated an association of sarcopenia with inflammatory markers CRP, erythrocyte sedimentation rate and adiponectin.

Fried frailty phenotype assessment components as applied to geriatric inpatients

J. Bieniek , K. Wilczyński and J. Szewieczek

Clin Interv Aging. 2016;11:453-9

The aim of this article was to assess the usefulness and limitations of Fried frailty phenotype criteria in geriatric inpatients, characterized by comorbidity and functional impairments, and to estimate the frailty phenotype prevalence in this group. Data obtained suggest that Fried frailty phenotype criteria can useful for geriatric inpatient assessment, despite diagnostic limitations

Disseminating a Clinically Effective Physical Activity Program to Preserve Mobility in a Community Setting for Older Adults

J. Laussen, C. Kowaleski, K. Martin, et al.

J Frailty Aging. 2016;5(2):82-7

The objective of this study is to assess the dissemination of an evidence-based PA program for older adults by evaluating program participation and its impact on mobility, strength and quality of life. Results obtained suggest that the dissemination of a clinically efficacious physical activity intervention into a community-based setting can improve mobility, strength and quality of life for older adults.