For researchers

Association of Hearing Impairment With Incident Frailty and Falls in Older Adults.

R.J. Kamil, J. Betz, B. Brott Powers et al.

Journal of Aging and Health. 2015

The hearing impairment (HI) is highly prevalent but undertreated in older adults and, although it contributes to frailty risk, it remains poorly studied.
This study aimed at determining whether HI in older adults is associated with the development of frailty and falls.
This study demonstrate that moderate or greater HI is associated with increased risk of developing frailty and that HI is associated with an increased annual risk of falling.

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Dairy Consumption and Risk of Frailty in Older Adults: A Prospective Cohort Study.

A. Lana, F. Rodriguez-Artalejo and E. Lopez-Garcia

J Am Geriatr Soc. 2015;63(9):1852-60

Some studies have found positive effects of dairy consumption in older people, but the evidence base for this recommendation remains scarce.
This study aimed to examining the association between consumption of dairy products and risk of frailty in community-dwelling older adults.
Data obtained shown that higher consumption of low-fat milk and yogurt are associated with lower risk of frailty and, specifically, lower risk of slow walking speed and weight loss.

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Energetics of Aging and Frailty: The FRADEA Study.

P. Abizanda, L. Romero, P.M. Sánchez-Jurado et al.

J Gerontol A Biol Sci Med Sci. 2015;(00)00:1-10

Resting metabolic rate (RMR) and total daily energy expenditure (TDEE) decrease with aging, but it is not known whether frailty modulates this association. Authors hypothesize that RMR and TDEE values are similar between younger and older nonfrail adults, whereas they are lower in older prefrail and frail compared with younger adults.
This study shows that frailty status modulates the energy requirements of aging. Frail and prefrail older adults present lower eRMR than nonfrail adults.

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Serum markers of inflammation and oxidative stress in sarcopenia.

B. Can, O. Kara, M.C. Kizilarslanoglu et al.

Aging Clin Exp Res. 2016 Aug 29. [Epub ahead of print]

The aim of the study was to evaluate the relationship between sarcopenia and biomarkers that may be involved in its pathogenesis and hence allow early detection.
The present study demonstrated an association of sarcopenia with inflammatory markers CRP, erythrocyte sedimentation rate and adiponectin.

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Neuromuscular function in different stages of sarcopenia.

T. Morat, K.J. Gilmore and C.L. Rice

Exp Gerontol. 2016 Apr 20;81:28-36.

This study applied the screening tool developed by the European Working Group on Sarcopenia in Older People (EWGSOP) on seniors aged over 65years and concurrently tested various laboratory-based indices of neuromuscular function.
Based on gait speed, handgrip strength and muscle mass all subjects were categorized into one of the three conceptual sarcopenia stages (pre-sarcopenia, sarcopenia, severe sarcopenia). The laboratory tests found neuromuscular differences among the 3 groups which generally supported the classification scheme and helped to illustrate some key factors that could explain differences in functional capacities.

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High Levels of Heavy Metals Increase the Prevalence of Sarcopenia in the Elderly Population

J.I. Yoo, Y.C. Ha, Y.K. Lee et al.

J Bone Metab. 2016 May;23(2):101-9.

Despite increasing concern regarding health problems as a result of environmental pollutants, no association of toxic heavy metals with sarcopenia has been demonstrated in the general population. In this article the association of heavy metals, including lead, mercury and cadmium, with sarcopenia in the Korean population was investigated.
This study demonstrates that high levels of blood lead, mercury and cadmium increase the prevalence of sarcopenia in both genders of elderly populations.

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