What are the main aims of the SPRINTT trial?
The SPRINTT project is the largest European clinical study aimed at investigating whether physical disability may be prevented in older subjects with physical frailty and sarcopenia.
Two interventions will be compared in the SPRINTT trial:
1) A multicomponent intervention, based on physical activity and nutrition counselling, with support of specific technological devices;
2) A healthy aging lifestyle education programme.
The study will be conducted in 1500 community-living people aged 70 years and older, across 10 European countries (17 recruitment sites across Europe). The duration of the clinical trial will last approximately 3 years.
Main inclusion criteria:
- Age ≥ 70 years old;
- Having reduced muscle mass, i.e. sarcopenia;
- Having reduced physical performance, measured using a combination of three tests: not losing balance in three different positions without arm support, usual gait speed in a 4 meter walk, total time needed to get up and sit down 5 times from a chair without using arms.
- Being able to walk 400 m in less than 15 minutes.
For more information contact the recruiting center nearest to you:

1) Catholic University of the Sacred Heart School of Medicine (Rome, Italy)
Dr. Francesco Landi tel. +39-06-3015-3921
2) IRCCS-INRCA (Ancona, Italy)
The SPRINT-T team Tel. +39-071-8003284 or +39-071-8003719
E-mail [email protected]
3) University of Parma (Parma, Italy)
Prof. Marcello Maggio Tel. +39-0521-903114
E-mail [email protected]
The SPRINT-T team Tel. +39-0521-9066424 or +39 0521 903111
E-mail [email protected] or
4) CHU Toulouse (Toulouse, France)
Dr. Agathe Milhet tel. +33-(0)561-77-7115
5) CHU Limoges (Limoges, France)
Prof. Thierry Dantoine tel. +33-(0)555-05-8626
6) Getafe University Hospital (Madrid, Spain)
Dr. Olga Laosa Zafra tel: 0034 916839360 (Ext 2689)
Prof. Leocadio Rodriguez Mañas tel: 0034 916839360 (Ext. 6412)
7) Hospital Universitario Ramón y Cajal (Madrid, Spain)
Dr. Alfonso Cruz Jentoft tel. +34-913-368-8172
8) Friedrich-Alexander Universität Erlangen-Nürnberg (Nürnberg, Germany)
Prof. Dr. Cornel Sieber tel. ++49-911-5302-96150
Dr. Ellen Freiberger tel. ++49-911-5302-96162
9) Charles University (Prague, Czech Republic)
Prof. Eva Topinkova tel. +420-22-251-42-94
10) Salesians Hospital (Opava, Czech Republic)
Dr. Ingrid Ryznarova tel. +420-553-766780
Dr. Jakub Seget
11) Jagiellonian University Medical College (Krakow, Poland)
Dr. Katarzyna Petitjean tel. +48-12-424-88-05
12) Diabetes Frail (Luton, UK)
Prof. Alan Sinclair tel. +44-07469-178232
13) Heart of England NHS Foundation Trust (Birmingham, UK)
Dr Sri Bellary tel. +44-0121-204-4145
14) Aston University (Birmingham, United Kingdom)
Dr Srikanth Bellary tel. 0044 121 424 2854
Dr. Nichola Seare tel. 0044 121 204 3325
15) University of Iceland (Reykjavík, Iceland)
Dr. Olof G. Geirsdottirtel. 00354-543-9898
16) University of Helsinki (Helsinki, Finland)
Dr Hanna Öhman tel. +358 50 5531528
17) Maastricht University Medical Center (Maastricht, The Netherlands)
Dr. Coby van de Boo tel. +31-43-388-13-24


