For Healthcare Providers

The Role of Muscle Mass Gain Following Protein Supplementation Plus Exercise Therapy in Older Adults with Sarcopenia and Frailty Risks: A Systematic Review and Meta-Regression Analysis of Randomized Trials

C.D. Liao, H.C. Chen, S.W. Huang, et al.

Nutrients. 2019;11(8). pii: E1713. doi: 10.3390/nu11081713.

Aging and frailty are associated with a high risk of lean mass (LM) loss, which leads to physical disability and can be effectively alleviated by protein supplementation (PS) and muscle strengthening exercise (MSE). In this study, the associations between LM gain and PS + MSE efficacy (measured using physical outcomes) in elderly patients with a high risk of sarcopenia or frailty were identified.

Medium-chain triglycerides (8:0 and 10:0) are promising nutrients for sarcopenia: a randomized controlled trial

S. Abe, O. Ezaki, M. Suzuki

Am J Clin Nutr. 2019 Jul 23. pii: nqz138. doi: 10.1093/ajcn/nqz138. [Epub ahead of print]

The combined supplementation of medium-chain triglycerides (MCTs), l-leucine-rich amino acids, and cholecalciferol was previously shown to increase muscle strength and function in frail elderly individuals.

We examined whether treatment with MCTs alone is sufficient to increase muscle strength and function and activities of daily living (ADL) in such individuals.

The impact of muscle function, muscle mass and sarcopenia on independent ageing in very old Swedish men

K. Franzon, B. Zethelius, T. Cederholm, et al.

BMC Geriatr. 2019;19(1):153

The aim of this study was to examine the impact of sarcopenia, and its underlying components, on independent ageing in a cohort study of very old men.

Malnutrition and sarcopenia

C.C. Sieber

Aging Clin Exp Res. 2019;31(6):793-798

Risk for or established malnutrition is frequent in older adults, accompanied by functional limitations, increased morbidity and mortality. Protein-energy malnutrition is often observed and leads besides other predisposing factors to sarcopenia, the increased loss of muscle mass with aging.

Exercise Interventions for the Prevention and Treatment of Sarcopenia. A Systematic Umbrella Review

D. Beckwée, A. Delaere, S. Aelbrecht, et al.

J Nutr Health Aging. 2019;23(6):494-502

The aim of this systematic review is to provide an overview of the efficacy of different exercise interventions to counter sarcopenia in older adults. This review will allow the Belgian Society of Gerontology and Geriatrics and other scientific societies to formulate specific exercise recommendations in their Clinical Guidelines for Sarcopenia.

A high whey protein, vitamin D and E supplement preserves muscle mass, strength, and quality of life in sarcopenic older adults: A double-blind randomized controlled trial

Y. Bo, C. Liu, Z. Ji, et al.

Clin Nutr. 2019;38(1):159-164

Sarcopenia, an age-related decline of muscle mass, strength, and physical function, was associated with falls, frailty, and poor quality of life. The aim of the current study is to examine the effect of nutritional supplement containing whey protein, vitamin D and E on measures of sarcopenia.

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