For Healthcare Providers

The Effect of β-hydroxy-β-methylbutyrate (HMB) on Sarcopenia and Functional Frailty in Older Persons: A Systematic Review

J. Oktaviana, J. Zanker, S. Vogrin, et al.

J Nutr Health Aging. 2019;23(2):145-150

Beta-hydroxy-beta-methylbutyrate (HMB) has been shown to be effective and superior to other types of protein supplements to attenuate loss of muscle mass, strength and function, however, its benefits in sarcopenic and frail older people remain unclear.

We seek to determine the effect of HMB on muscle mass, strength and function in older people with sarcopenia or frailty by reviewing results from available randomized controlled trials (RCTs).

Effects of branched-chain amino acids and vitamin D supplementation on physical function, muscle mass and strength, and nutritional status in sarcopenic older adults undergoing hospital-based rehabilitation: A multicenter randomized controlled trial

I. Takeuchi, Y. Yoshimura, S. Shimaz, et al.

Geriatr Gerontol Int. 2019;19(1):12-17

The aim was to investigate the effects of branched-chain amino acids and vitamin D supplementation on physical function, muscle strength, muscle mass, and nutritional status in sarcopenic older adults undergoing hospital-based rehabilitation.

Higher dietary nitrate intake is associated with better muscle function in older women

M. Sim, J.R. Lewis, L.C. Blekkenhorst, et al.

J Cachexia Sarcopenia Muscle. 2019 Mar 24. doi: 10.1002/jcsm.12413. [Epub ahead of print]

The role of higher habitual nitrate intake as part of a typical diet on muscle function in ageing has not been investigated. In this article a cross-sectional study of relationships between dietary nitrate and measures of muscle function in older community-dwelling Australian women (n = 1420, ≥70 years) was undertaken.

Leucine co-ingestion augments the muscle protein synthetic response to the ingestion of 15 g protein following resistance exercise in older men

A.M. Holwerda, K.J.M. Paulussen, M. Overkamp, et al.

Am J Physiol Endocrinol Metab. 2019 May 21. doi: 10.1152/ajpendo.00073.2019. [Epub ahead of print]

We investigated whether co-ingestion of 1.5 g free leucine with a single, 15 g bolus of protein further augments the post-prandial muscle protein synthetic response during recovery from resistance-type exercise in older men.

Consequences of applying the new EWGSOP2 guideline instead of the former EWGSOP guideline for sarcopenia case finding in older patients

J. Reiss, B. Iglseder, R. Alzner, et al.

Age Ageing. 2019 May 21. pii: afz035. doi: 10.1093/ageing/afz035. [Epub ahead of print]

We examined the consequences of applying the new EWGSOP2 algorithm for sarcopenia screening instead of the former EWGSOP algorithm (EWGSOP1) in geriatric inpatients.

Effects of higher habitual protein intake on resistance-training-induced changes in body composition and muscular strength in untrained older women: A clinical trial study

H.C. Nabuco, C.M. Tomeleri, P.S. Junior, et al.

Nutr Health. 2019;25(2):103-112

Aging is accompanied by progressive and accentuated decline in muscular strength and skeletal muscle mass, affecting health and functional autonomy. Both resistance training (RT) and diet are strategies that may contribute to improvement in the health of the elderly.

The purpose of this study was to evaluate the effects of higher habitual protein intake on RT-induced changes in body composition and strength in untrained postmenopausal women.

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