5. How will this project contribute to solving the problem?

The SPRINTT project is geared to produce significant advancements in the management of frail elders by promoting a consensus among academia, regulators, industry, and patients’ representatives over

(1) clear operationalization of the presently vague concept of frailty;

(2) identification of a precise target population with unmet medical needs;

(3) evaluation and validation of a new methodology for implementing in Europe preventive and therapeutic strategies among frail elders at risk of disability;

(4) definition of an experimental setting serving as template for regulatory purposes and pharmaceutical investigations;

(5) identification of biomarkers and m-health technology solutions to be implemented into clinical practice.