For Researchers

Effect of Protein Intake on Lean Body Mass in Functionally Limited Older Men

S. Bhasin, C.M. Apovian, T.G. Travison, et al.

JAMA Intern Med. 2018;178(4):530-541

This study aimed at investigating whether increasing protein intake to 1.3 g/kg/d in older adults with physical function limitations compared with usual protein intake within the RDA (0.8 g/kg/d) improves lean body mass (LBM), muscle performance, physical function, fatigue, and well-being and augments LBM response to a muscle anabolic drug.



Maintenance of Physical Function 1 Year After Exercise Intervention in At-Risk Older Adults: Follow-up From the LIFE Study

R.M. Henderson, M.E. Miller, R.A. Fielding, et al.

J Gerontol A Biol Sci Med Sci. 2018;73(5):688-694

Structured physical activity interventions delay the onset of disability for at-risk older adults. However, it is not known if at-risk older adults continue to participate in physical activity or maintain mobility benefits after cessation of structured intervention.


Impact of Sarcopenia on One-Year Mortality among Older Hospitalized Patients with Impaired Mobility

M. Pourhassan, K. Norman, M.J. Müller, et al.

J Frailty Aging. 2018;7(1):40-46

The aim of the present study was to investigate the associations between sarcopenia and 1-year mortality in a prospectively recruited sample of geriatric inpatients with different mobility and dependency status.



Risk of Malnutrition Evaluated by Mini Nutritional Assessment and Sarcopenia in Noninstitutionalized Elderly People

I. Liguori, F. Curcio, G. Russo, et al.

Nutr Clin Pract. 2018 Feb 13. doi: 10.1002/ncp.10022. [Epub ahead of print]

Malnutrition indices and muscle mass and strength in the elderly are poorly investigated. Moreover, malnutrition seems to be one of the more important factors in the cause of sarcopenia.

The presence of sarcopenia and its relationship with malnutrition indices were studied in noninstitutionalized elderly people who underwent Comprehensive Geriatric Assessment (CGA).


Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia

K. Sakuma and A. Yamaguchi

Pflugers Arch. 2018;470(3):449-460

The article is composed of the data reported in many basic and some clinical studies for mammalian muscles.


Potential roles of vitamin E in age-related changes in skeletal muscle health

E. Chung, H. Mo, S. Wang, et al.

Nutr Res. 2018;49:23-36

Current literature suggests that vitamin E molecules (α-, β-, γ-, δ-tocopherols and the corresponding tocotrienols) with their antioxidant and anti-inflammatory capabilities may mitigate age-associated skeletal dysfunction and enhance muscle regeneration, thus attenuating sarcopenia.