For Researchers

Epidemiology of Sarcopenia and Factors Associated With It Among Community-Dwelling Older Adults in Taiwan

Y.H. Kuo, T.F. Wang, L.K. Liu, et al.

Am J Med Sci. 2019;357(2):124-133

Sarcopenia is a well-recognized geriatric syndrome. We sought to determine the prevalence of sarcopenia and factors associated with it among community-dwelling older adults in Taiwan.

Decreased Basal Metabolic Rate Can Be an Objective Marker for Sarcopenia and Frailty in Older Males

P. Soysal, E. Ates Bulut, I. Yavuz, et al.

J Am Med Dir Assoc. 2019;20(1):58-63

The aim of this study is to demonstrate the ability of the basal metabolic rate (BMR) to detect frailty and sarcopenia in older males.

Changes in frailty status in a community-dwelling cohort of older adults: The VERISAÚDE study

L. Lorenzo-López, R. López-López, A. Maseda, et al.

Maturitas. 2019;119:54-60

Greater understanding of changes in the degree of frailty is important for clarifying the natural history of frailty and may help clinical decision-making regarding preventive interventions. The objectives of this study were to explore natural frailty transition rates at 1-year follow-up and to identify the main determinants of such transitions.

Dietary Factors Associated with Frailty in Old Adults: A Review of Nutritional Interventions to Prevent Frailty Development

J.J. Hernández Morante, C. Gómez Martínez, J.M. Morillas-Ruiz

Nutrients. 2019;11(1). pii: E102. doi: 10.3390/nu11010102

As the population ages, the need for specialised geriatric care will increase immensely, and consequently, the need for specialised services for the care of these people will increase accordingly. From a nutritional point of view, to control or balance the nutritional status of residents will be essential in order to prevent sarcopenia and, consequently, frailty development.

Systemic and Metabolic Signature of Sarcopenia in Community-Dwelling Older Adults

Y. Lu, L.G. Karagounis, T.P. Ng, et al.

J Gerontol A Biol Sci Med Sci. 2019 Jan 8. doi: 10.1093/gerona/glz001. [Epub ahead of print]

The present cross-sectional study characterized the nutritional and metabolic profile of sarcopenia through an extensive exploration of a wide array of blood biomarkers related to muscle protein metabolism and transcriptomic signatures in community-dwelling elderly.

Targeting mitochondrial quality control for treating sarcopenia: lessons from physical exercise

A. Picca, R. Calvani, C. Leeuwenburgh, et al.

Expert Opin Ther Targets. 2019;23(2):153-160

We discuss the evidence that points to mitochondrial dysfunction having a causative role in sarcopenia and the mechanisms involved in the accumulation of damaged mitochondria in the aged muscle. We also discuss the effects of physical exercise on mitochondrial quality control and muscle health in advanced age.