For Researchers

Sarcopenia in Community-Dwelling Oldest Old Is Associated with Disability and Poor Physical Function

W. Xu, T. Chen, Y. Cai, et al.

J Nutr Health Aging. 2020;24(23):339-345. doi: 10.1007/s12603-020-1325-4.

Sarcopenia is an age-related geriatric syndrome and is associated with numerous adverse outcomes. Although there is preponderance of studies on sarcopenia in community setting, few studies focused on the oldest old. We investigated the prevalence of sarcopenia in Chinese community-dwelling oldest old and examined the socio-demographic and lifestyle factors of sarcopenia. We also investigated the association between sarcopenia and disability in activities of daily living (ADL) and physical function among the oldest old.

Circulating Micronutrient Biomarkers Are Associated With 3 Measures of Frailty: Evidence From the Irish Longitudinal Study on Ageing

A.M. O'Halloran, E.J. Laird, J. Feeney, et al.

J Am Med Dir Assoc. 2020;21(2):240-247.e5. doi: 10.1016/j.jamda.2019.06.011. Epub 2019 Aug 7.

The aim was to examine the associations between 3 frailty instruments and circulating micronutrients in a large representative sample of older adults.

Association of fatty acid consumption with frailty and mortality among middle-aged and older adults

K. Jayanama, O. Theou, J. Godin, et al.

Nutrition. 2020;70:110610. doi: 10.1016/j.nut.2019.110610. Epub 2019 Oct 11.

Despite their role in health and disease, the relationship between fatty acids (FAs) and frailty and mortality remains unclear. The aim of this study was to explore how FA intake is associated with frailty and mortality.

Exploring the potential of salivary and blood immune biomarkers to elucidate physical frailty in institutionalized older women

G.E. Furtado, M. Uba Chupel, L. Minuzzi, et al.

Exp Gerontol. 2020;129:110759. doi: 10.1016/j.exger.2019.110759. Epub 2019 Oct 31.

Identification of older populations at increased risk of physical frailty using biochemical approaches could improve screening accuracy. The aim of this study was to study the relationship between immune markers and independent components of physical frailty in institutionalized older women.

The accumulation of deficits approach to describe frailty

R. Lachmann, M. Stelmach-Mardas, M.M. Bergmann, et al.

PLoS One. 2019 Oct 15;14(10):e0223449. doi: 10.1371/journal.pone.0223449. eCollection 2019

The advancing age of the participants of the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam study was the incentive to investigate frailty as a major parameter of ageing. The aim of this study was to develop a multidimensional tool to measure frailty in an ageing, free-living study population.

Beneficial Effects of Leucine Supplementation on Criteria for Sarcopenia: A Systematic Review

F.M. Martínez-Arnau, R. Fonfría-Vivas, O. Cauli

Nutrients. 2019 Oct 17;11(10)

Treating sarcopenia remains a challenge, and nutritional interventions present promising approaches. We summarize the effects of leucine supplementation in treating older individuals with sarcopenia associated with aging or to specific disorders, and we focus on the effect of leucine supplementation on various sarcopenia criteria, e.g., muscular strength, lean mass, and physical performance.

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