For Researchers

Exercise interventions in healthy older adults with sarcopenia: A systematic review and meta-analysis

L. Vlietstra, W. Hendrickx, D.L. Waters

Australas J Ageing. 2018 Apr 11. doi: 10.1111/ajag.12521. [Epub ahead of print]

Exercise interventions significantly improved strength, balance and muscle mass. However, the number of trials was small and the training effect was inconsistent due to heterogeneity in exercise mode, duration and intensity. Lack of detailed description makes it impossible to reflect on the progressive resistance training approaches used. More research is needed to confirm these findings.

 

 

Frailty and multimorbidity: a systematic review and meta-analysis

D.L. Vetrano, K. Palmer, A. Marengoni, et al.

J Gerontol A Biol Sci Med Sci. 2018 May 3. doi: 10.1093/gerona/gly110. [Epub ahead of print]

Frailty and multimorbidity are two related conditions in older adults. Most frail individuals are also multimorbid but fewer multimorbid ones present also frailty.

Our findings are not conclusive regarding the causal association between the two conditions. Further longitudinal and well-designed studies may help to untangle the relationship between frailty and multimorbidity.

 

 

The Impact of Dietary Factors on Indices of Chronic Disease in Older People: A Systematic Review

C.A. Nowson, C. Service, J. Appleton, et al.

J Nutr Health Aging. 2018;22(2):282-296

The aims of this sudy were to i) conduct a systematic review of studies assessing dietary factors in relation to six key functional indicators which impact on quality of life in adults ≥65 yrs: non-fatal cardiovascular events, cognition, mental health, falls and fractures, physical health (muscle mass, strength) and frailty; and ii) assess if there was sufficient evidence to devise food-based dietary recommendations.

 

 

This umbrella review aimed to determine the effectiveness of exercise interventions, alone or in combination with other interventions, in improving physical function in community-dwelling older people identified as pre-frail or frail

A.D. Jadczak, N. Makwana, N. Luscombe-Marsh, et al.

JBI Database System Rev Implement Rep. 2018;16(3):752-775

This umbrella review aimed to determine the effectiveness of exercise interventions, alone or in combination with other interventions, in improving physical function in community-dwelling older people identified as pre-frail or frail.

 

 

Grip strength measurement for frailty assessment in patients with vascular disease and associations with comorbidity, cardiac risk, and sarcopenia

T.E. Reeve, R. Ur, T.E. Craven, et al.

J Vasc Surg. 2018;67(5):1512-1520

Frailty measures based on walking-based tests may be impractical or invalid for patients with walking impairment from symptoms or sequelae of vascular disease. We hypothesized that grip strength is associated with frailty, comorbidity, and cardiac risk among patients with vascular disease.

 

 

Sufficient levels of 25-hydroxyvitamin D and protein intake required to increase muscle mass in sarcopenic older adults - The PROVIDE study

S. Verlaan, A.B. Maier, J.M. Bauer, et al.

Clin Nutr. 2018;37(2):551-557

This study wants to test if baseline serum 25-hydroxyvitamin D (25(OH)D) concentrations and dietary protein intake influenced changes in muscle mass and function in older adults who received nutritional intervention.

 

 

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