For Researchers

Sarcoscore: A Novel Approach for Assessing Sarcopenia and Functional Disability in Older Adults

Y. Osuka, H. Kim, H. Kawai,et al.

J Clin Med. 2020;9(3). pii: E692. doi: 10.3390/jcm9030692.

We developed an index for assessing sarcopenia degree (sarcoscore) and compared it to the Asian Working Group for Sarcopenia (AWGS) criteria.

Circulating Interleukin-6 Is Associated with Skeletal Muscle Strength, Quality, and Functional Adaptation with Exercise Training in Mobility-Limited Older Adults

G.J Grosicki, B.B. Barrett, D.A. Englund,et al.

J Frailty Aging. 2020;9(1):57-63. doi: 10.14283/jfa.2019.30.

The aim was to investigate relationships between circulating IL-6, skeletal muscle health and exercise adaptation in mobility-limited older adults.

Sarcopenia Definition: The Position Statements of the Sarcopenia Definition and Outcomes Consortium

S. Bhasin, T.G. Travison, T.M. Maniniz, et al.

J Am Geriatr Soc. 2020 Mar 9. doi: 10.1111/jgs.16372. [Epub ahead of print]

The aim was to develop an evidence-based definition of sarcopenia that can facilitate identification of older adults at risk for clinically relevant outcomes (eg, self-reported mobility limitation, falls, fractures, and mortality), the Sarcopenia Definition and Outcomes Consortium (SDOC) crafted a set of position statements informed by a literature review and SDOC's analyses of eight epidemiologic studies, six randomized clinical trials, four cohort studies of special populations, and two nationally representative population-based studies.

The Tilburg Frailty Indicator (TFI): New Evidence for Its Validity

R.J. Gobbens, P. Boersma, I. Uchmanowicz, et al.

Clin Interv Aging. 2020;15:265-274

The Tilburg Frailty Indicator (TFI) is a self-report user-friendly questionnaire for assessing multidimensional frailty among community-dwelling older people. The main aim of this study is to re-evaluate the validity of the TFI, both cross-sectionally and longitudinally, focusing on the predictive value of the total TFI and its physical, psychological, and social domains for adverse outcomes disability, indicators of healthcare utilization, and falls.

Protein-Related Dietary Parameters and Frailty Status in Older Community-Dwellers across Different Frailty Instruments

H.J. Coelho-Júnior, R. Calvani, A. Picca, et al.

Nutrients. 2020;12(2). pii: E508. doi: 10.3390/nu12020508.

The present study investigated the associations between frailty status and (a) daily protein intake, (b) daily body weight-adjusted protein intake, (c) branched-chain amino acid (BCAA) consumption, (d) evenness of protein distribution across main meals, (e) number of daily meals providing at least 30 g of protein, and (f) number of daily meals providing at least 0.4 g protein/kg of body weight in community-dwelling older adults. The relationship between frailty status and protein-related dietary parameters was explored across different frailty assessment tools.

Sarcopenia in Community-Dwelling Oldest Old Is Associated with Disability and Poor Physical Function

W. Xu, T. Chen, Y. Cai, et al.

J Nutr Health Aging. 2020;24(23):339-345. doi: 10.1007/s12603-020-1325-4.

Sarcopenia is an age-related geriatric syndrome and is associated with numerous adverse outcomes. Although there is preponderance of studies on sarcopenia in community setting, few studies focused on the oldest old. We investigated the prevalence of sarcopenia in Chinese community-dwelling oldest old and examined the socio-demographic and lifestyle factors of sarcopenia. We also investigated the association between sarcopenia and disability in activities of daily living (ADL) and physical function among the oldest old.

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