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Recent advances in pharmacological, hormonal, and nutritional intervention for sarcopenia

K. Sakuma and A. Yamaguchi

Pflugers Arch. 2018;470(3):449-460

The article is composed of the data reported in many basic and some clinical studies for mammalian muscles.

 

Potential roles of vitamin E in age-related changes in skeletal muscle health

E. Chung, H. Mo, S. Wang, et al.

Nutr Res. 2018;49:23-36

Current literature suggests that vitamin E molecules (α-, β-, γ-, δ-tocopherols and the corresponding tocotrienols) with their antioxidant and anti-inflammatory capabilities may mitigate age-associated skeletal dysfunction and enhance muscle regeneration, thus attenuating sarcopenia.

 

Cross-sectional associations of dietary and circulating magnesium with skeletal muscle mass in the EPIC-Norfolk cohort

R.P.G. Hayhoe, M.A.H. Lentjes, A.A. Mulligan, et al.

Clin Nutr. 2018 Jan 30. pii: S0261-5614(18)30015-3. doi: 10.1016/j.clnu.2018.01.014. [Epub ahead of print]

This study demonstrated strong associations between dietary magnesium intake, but not serum magnesium levels, and indices of skeletal muscle mass in a UK population of middle to older-aged adults, highlighting the likely importance of dietary magnesium for optimal muscle health in this population.

 

Prevalence of muscle weakness based on different diagnostic criteria in community-dwelling older adults: a comparison of grip strength dynamometers

M. Kim and S. Shinkai

Geriatr Gerontol Int. 2017;17(11)2089-2095

The present study compared the performance of the Jamar and Smedley dynamometers for the measurement of grip strength, and the two dynamometers were used to determine the prevalence rate of weakness in a large, community-dwelling, older adult population, based on different diagnostic criteria.

 

Resveratrol enhances exercise-induced cellular and functional adaptations of skeletal muscle in older men and women

S.E. Alway, J.L. McCrory, K. Kearcher, et al.

J Gerontol A Biol Sci Med Sci. 2017;72(12):1595-1606

Data obtained indicate a novel anabolic role of resveratrol in exercise-induced adaptations of older persons and this suggests that resveratrol combined with exercise might provide a better approach for reversing sarcopenia than exercise alone.

 

Vitamin B12 deficiency might be related to sarcopenia in older adults

E.A. Bulut, P. Soysal, A.E. Aydin, et al.

Exp Gerontol. 2017; 95:136-140

The aim of this study is to evaluate the relationship between vitamin B12 deficiency and sarcopenia in older adults.

 

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