For Researchers

Longitudinal Associations Between Walking Speed and Amount of Self-reported Time Spent Walking Over a 9-Year Period in Older Women and Men

J.R. Best, T. Liu-Ambrose, A.L. Metti, et al.

J Gerontol A Biol Sci Med Sci. 2018;73(9):1265-1271

In this longitudinal study, we hypothesized that early mobility limitations would contribute to later decreases in physical activity to a larger degree than the reciprocal association of early decreases in physical activity to later mobility limitations.

Identification of frailty by the use of the SEGAm scale (part A) in geriatrical consultation

A.A. Zulfiqar

Geriatr Psychol Neuropsychiatr Vieil. 2018;16(3):269-277

A prospective, observational study was performed in subjects aged over 75 years, coming from the first neuro-geriatric consultation, from July 3, 2017 to August 18, 2017, included in the CHU Rouen, and benefiting from frailty screening through the use of the grid SEGAm (part A); this correlated with the subjective opinion of the nurse.

Comparing Mini Sarcopenia Risk Assessment With SARC-F for Screening Sarcopenia in Community-Dwelling Older Adults

M. Yang, X. Hu, L. Xie, et al.

J Am Med Dir Assoc. 2018 Jun 13. pii: S1525-8610(18)30229-9. doi: 10.1016/j.jamda.2018.04.012. [Epub ahead of print]

The Mini Sarcopenia Risk Assessment (MSRA), a new sarcopenia screening tool, has 2 versions: MSRA-7 (full version, 7 items) and MSRA-5 (short version, 5 items).

We aimed to compare the diagnostic values of MSRA-7 and MSRA-5 to SARC-F for screening sarcopenia.

SARC-F for sarcopenia screening in community-dwelling older adults: Are 3 items enough?

M. Yang, X. Hu, L. Xie, et al.

Medicine (Baltimore). 2018;97(30):e11726

A 3-item SARC-F (termed SARC-F-3 in our study) was recently suggested as a screening tool for sarcopenia.

The aim of this study was to compare the diagnostic value of SARC-F-3 to SARC-F in community-dwelling older people.

A free radical theory of frailty

J. Viña, C. Borras and M.C. Gomez-Cabrera

Free Radic Biol Med. 2018 Jun 26;124:358-363

In this review, we describe results from both, experimental animals and human cohorts, that lead us to the formulate this free radical theory of frailty.

The age-related loss of skeletal muscle mass and function: measurement and mechanisms of muscle fibre atrophy and muscle fibre loss in humans

D.J. Wilkinson, M. Piasecki and P.J. Atherton

Ageing Res Rev. 2018;47:123-132

This review will focus on muscle deterioration with ageing and highlight the two underpinning mechanisms regulating declines in muscle mass and function: muscle fibre atrophy and muscle fibre loss (hypoplasia) - and their measurement.