For Healthcare Providers

Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta-analysis

S.S.Y. Yeung, E.M. Reijniers, V.K. Pham, et al.

J Cachexia Sarcopenia Muscle. 2019 Apr 16. doi: 10.1002/jcsm.12411. [Epub ahead of print]

Sarcopenia is a potentially modifiable risk factor for falls and fractures in older adults, but the strength of the association between sarcopenia, falls, and fractures is unclear. This study aims to systematically assess the literature and perform a meta-analysis of the association between sarcopenia with falls and fractures among older adults.

Gait speed as a mediator of the effect of sarcopenia on dependency in activities of daily living

M.A. Perez-Sousa, L.C. Venegas-Sanabria, D.A. Chavarro-Carvajal, et al.

J Cachexia Sarcopenia Muscle. 2019 May 8. doi: 10.1002/jcsm.12444. [Epub ahead of print]

Sarcopenia in older adults is strongly associated with an increase in dependency in activities of daily living (ADL) and with a decline in gait speed. Interestingly, gait speed has been shown to independently predict mortality. In this context, our study aimed to explore the mediator role of gait speed on the relationship between sarcopenia and dependency in ADL.

Sex-specific differences in the association of vitamin D with low lean mass and frailty: Results from the Berlin Aging Study II

D. Spira, N. Buchmann, M. König, et al.

Nutrition. 2019;62:1-6

Sex-specific differences in factors associated with aging and lifespan, such as sarcopenia and disease development, are increasingly recognized. The study aims to assess sex-specific aspects of the association between vitamin D insufficiency and low lean mass as well as between vitamin D insufficiency and the frailty phenotype.

Impact of Sarcopenia and Frailty in a Multicenter Cohort of Polypathological Patients

M. Bernabeu-Wittel, Á. González-Molina, R. Fernández-Ojeda, et al.

J Clin Med. 2019 Apr 18;8(4). pii: E535. doi: 10.3390/jcm8040535.

We performed a multicenter prospective observational study in six hospitals in order to assess prevalence, clinical features, outcome and associated risk factors of sarcopenia and frailty in a hospital-based population of polypathological patients.

Ultrasound measurement of rectus femoris muscle thickness as a quick screening test for sarcopenia assessment

K. Rustani, L. Kundisova, P.L. Capecchi, et al.

Arch Gerontol Geriatr. 2019;83:151-154

According to European Working Group on Sarcopenia in Older People (EWGSOP) the diagnosis of sarcopenia requires the assessment of muscle mass, muscle force and function, that is time-consuming and not easily at hand in everyday clinical practice. We propose the B-mode ultrasound measurement of muscle thickness as a quick screening test to assess the presence of sarcopenia.

Circulating factors associated with sarcopenia during ageing and after intensive lifestyle intervention

C.W. Li, K. Yu, N. Shyh-Chang, et al.

J Cachexia Sarcopenia Muscle. 2019 Apr 10. doi: 10.1002/jcsm.12417. [Epub ahead of print]

In this study, we evaluated whether proinflammatory cytokines are associated with the onset of sarcopenia, which circulating factors are associated with the severity of sarcopenia, and how these factors change after lifestyle interventions in sarcopenic elderly persons.