For Healthcare Providers

Physical activity and exercise: Strategies to manage frailty

J. Angulo, M. El Assar, A. Álvarez-Bustos, et al.

Redox Biol. 2020 Mar 20:101513. doi: 10.1016/j.redox.2020.101513. [Epub ahead of print]

Frailty, a consequence of the interaction of the aging process and certain chronic diseases, compromises functional outcomes in the elderly and substantially increases their risk for developing disabilities and other adverse outcomes. Frailty follows from the combination of several impaired physiological mechanisms affecting multiple organs and systems. And, though frailty and sarcopenia are related, they are two different conditions. Thus, strategies to preserve or improve functional status should consider systemic function in addition to muscle conditioning. Physical activity/exercise is considered one of the main strategies to counteract frailty-related physical impairment in the elderly.

Effects of Leucine Administration in Sarcopenia: A Randomized and Placebo-controlled Clinical Trial

F.M. Martínez-Arnau, R. Fonfría-Vivas, C. Buigues, et al.

Nutrients. 2020 Mar 27;12(4). pii: E932. doi: 10.3390/nu12040932.

We assessed the efficacy of leucine administration to evaluate whether the regular intake of this essential amino acid can improve muscle mass, muscle strength and functional performance and respiratory muscle function in institutionalized older individuals.

Factors associated with sarcopenia: A cross-sectional analysis using UK Biobank

F. Petermann-Rocha, M. Chen, S.R. Gray, et al.

Maturitas. 2020 Mar;133:60-67. doi: 10.1016/j.maturitas.2020.01.004. Epub 2020 Jan 8.

The critical sociodemographic, lifestyle and diseases factors influencing sarcopenia, defined by the current European Working Group on Sarcopenia 2 (EWGSOP2) classification and cut-off points, have not yet been fully elucidated. This study aimed, therefore, to determine sociodemographic, anthropometric, lifestyle and health-related factors associated with sarcopenia using the new EWGSOP2 definition.

The effect of ageing on skeletal muscle as assessed by quantitative MR imaging: an association with frailty and muscle strength

M. Farrow, J. Biglands, S.F. Tanner, et al.

Aging Clin Exp Res. 2020 Mar 20. doi: 10.1007/s40520-020-01530-2. [Epub ahead of print]

The aim was to investigate whether quantitative MRI measures of T2, fat fraction (FF), diffusion tensor imaging and muscle volume can detect differences within the muscles between three age groups, and to assess how these measures compare with frailty index, gait speed and muscle power.

Differences in the Prevalence of Sarcopenia in Community-Dwelling, Nursing Home and Hospitalized Individuals. A Systematic Review and Meta-Analysis

S.K. Papadopoulou, P. Tsintavis, P. Potsaki, et al.

J Nutr Health Aging. 2020;24(1):83-90. doi: 10.1007/s12603-019-1267-x.

The current systematic review and meta-analysis study was carried out to estimate the overall prevalence of sarcopenia in both males and females in different regions around the world and to show the major differences in its occurrence among different populations.

Novel Insights on Intake of Fish and Prevention of Sarcopenia: All Reasons for an Adequate Consumption

M. Rondanelli, C. Rigon, S. Perna, et al.

Nutrients. 2020 Jan 24;12(2). pii: E307. doi: 10.3390/nu12020307.

This narrative literature review was performed to evaluate evidence regarding the actual benefit of fish consumption in the prevention of sarcopenia and the positive action on the muscle mass of the biological compounds present in fish.