Für medizinische Dienstleister

Depression and frailty in later life: a systematic review

L. Vaughan, A.L. Corbin, J.S. Goveas

Clin Interv Aging. 2015;10:1947-58

Frailty and depression are important issues affecting older adults. Depressive syndrome may be difficult to clinically disambiguate from frailty in advanced old age. This review examined the published literature on cross-sectional and longitudinal associations between frailty and depressive symptomatology.

Prospective relationship between depressive symptomatology and increased risk of incident frailty was robust, while the opposite relationship was less conclusive. The presence of comorbidities that interact with depressive symptomatology increased incident frailty risk.

Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: A case-control study

S. Verlaan, T.J. Aspray, J.M. Bauer, et al.

Clin Nutr. 2017; 36(1):267-274

The aim of this study was to compare functional and nutritional status, body composition, and quality of life of older adults between age and sex-matched older adults with and without sarcopenia.

In non-malnourished older adults with and without sarcopenia, it was observed that sarcopenia substantially impacted self-reported quality of life and physical activity levels. Differences in nutrient concentrations and dietary intakes were identified, which might be related to the differences in muscle mass, strength and function between the two groups.

Interventions for Treating Sarcopenia: A Systematic Review and Meta-Analysis of Randomized Controlled Studies

Y. Yoshimura, H. Wakabayashi, M. Yamada, et al.

J Am Med Dir Assoc. 2017; 18(6):553.e1-553.e16

This systematic review and meta-analysis showed some positive effects of exercise and nutritional interventions for treating sarcopenia in older people. According to interaction models, prefrail or frail individuals aged ≥67 years presented more prominent neuroimaging signatures of diffuse cortical or subcortical damage than their robust counterparts.

 

Neuroimaging signatures of frailty: A population-based study in community-dwelling older adults (the Atahualpa Project)

O.H. Del Brutto, R.M. Mera, K. Cagino, et al.

Geriatr Gerontol Int. 2017;17(2):270-276

The present study identifies neuroimaging signatures in older adults interviewed with the Edmonton Frail Scale (EFS).

According to interaction models, prefrail or frail individuals aged ≥67 years presented more prominent neuroimaging signatures of diffuse cortical or subcortical damage than their robust counterparts.

Nonpharmacological interventions to treat physical frailty and sarcopenia in older patients: a systematic overview - the SENATOR Project ONTOP Series

I. Lozano-Montoya, A. Correa-Pérez, I. Abraha, et al.

Clin Interv Aging. 2017;12:721-740

This overview of systematic reviews highlights the importance of exercise interventions with or without nutritional supplementation to improve the physical performance in community-dwelling patients aged >65 years with physical frailty and sarcopenia. Muscle strength was improved with multidisciplinary treatment and exercise interventions in this population.

 

What is the duration of life expectancy in the state of frailty? Estimates in the SIPAF study

M. Herr, J.J. Arvieu, J. Ankri, et al.

Eur J Ageing. 2017;15(2):165-173

This study aimed to estimate the time spent in the state of frailty in men and women using the Sullivan method.

In conclusion, frailty is a transition state that is relatively limited in time compared to pre-frailty that may represent a larger time window for prevention.  

Pages