Für medizinische Dienstleister

Nutritional interventions to prevent and treat frailty

A.J. Cruz-Jentoft, J. Woo

Curr Opin Clin Nutr Metab Care. 2019 Feb 18. doi: 10.1097/MCO.0000000000000556. [Epub ahead of print]

Frailty is a multidimensional condition common in older adults, where reduced resiliency leads to adverse outcomes. It has strong links with malnutrition and sarcopenia, mostly through muscle health. This review explores the links between nutrition and frailty from different perspectives.

Can Physical Activity Offset the Detrimental Consequences of Sedentary Time on Frailty? A Moderation Analysis in 749 Older Adults Measured With Accelerometers

A. Mañas, B.D. Pozo-Cruz, I. Rodríguez-Gómez, et al.

J Am Med Dir Assoc. 2019 Feb 6. pii: S1525-8610(18)30719-9. doi: 10.1016/j.jamda.2018.12.012. [Epub ahead of print]

The Johnson-Neyman technique determined that the estimated moderate-to-vigorous physical activity point was 27.25 minutes/d, from which sedentary time has no significant effect on frailty.

The feasibility of assessing frailty and sarcopenia in hospitalised older people: a comparison of commonly used tools

K. Ibrahim, F.F.A. Howson, D.J. Culliford, et al.

BMC Geriatr. 2019;19(1):42

Frailty and sarcopenia are common amongst hospitalised older people and associated with poor healthcare outcomes. Widely recognised tools for their identification are the Fried Frailty Phenotype, its self-report version the FRAIL Scale, and the European Working Group on Sarcopenia in Older People (EWGSOP) criteria. We studied the feasibility of using these tools in a hospital setting of acute wards for older people.

Exercise training increases skeletal muscle strength independent of hypertrophy in older adults aged 75 years and older

H. Lee, I.G. Kim, C. Sung, et al.

Geriatr Gerontol Int. 2019;19(3):265-270

We investigated whether exercise-mediated acquisition of muscle mass and strength would occur in a concurrent manner in older adults.

A total of 152 community-dwelling older adults (young-old aged 65-74 years, old-old aged >75 years) were allocated into either 8-week comprehensive exercise training or the control group.

The role of omega-3 in the prevention and treatment of sarcopenia

J. Dupont, L. Dedeyne, S. Dalle, et al.

Aging Clin Exp Res. 2019 Feb 19. doi: 10.1007/s40520-019-01146-1. [Epub ahead of print]

This narrative review provides an overview of the current knowledge about omega-3 PUFAs and their role in the prevention and treatment of sarcopenia. We conclude that there is growing evidence for a beneficial effect of omega-3 PUFAs supplementation in sarcopenic older persons, which may add to the effect of exercise and/or protein supplementation.

Prevalence of frailty in older people in Veneto (Italy)

A. Battaggia, A. Scalisi, B. Franco Novelletto, et al.

J Drug Assess. 2019;8(1):1-12

Both frailty and multimorbidity are strong predictors of clinical endpoints for older people. In Italy, the interventions targeting chronicity are mainly based on the treatment of diseases: sufficient epidemiological literature is available about these strategies. Less is known about the territorial distribution of the frailty status.

This study aimed at estimating the prevalence of frailty in older people (65+) and evaluating the relationship between frailty and multimorbidity.